Aim Mesenchymal stem cells discovered recently is a kind of adult stemcells derived from mesoblast. It has the commonness of stem cells that is capable of self-renewal and differentiating into many cell lineages. 目的:间充质干细胞(MesenchymalStemcells,MSC)是近年发现的来源于中胚层的一类非造血成体干细胞,具有干细胞的共性:高度自我更新和多向分化能力。
Adipocyte is originated from Mesenchymal stem cell which resides in mesoblast. It is mainly distributed in fat tissue and bone marrow which can differentiate into adipocyte, osteoblasts and cartilage. 脂肪细胞是由中胚层的间充质干细胞(mesenchymalstemcell,MSC)分化而来,MSC主要分布于脂肪组织和骨髓中,能分化为脂肪细胞、造骨细胞和软骨细胞。
It has been proved that BMSCs could transdifferentiate into mesoblast and endoblast cells in vitro. 以证实骨髓基质细胞可在体外转化成中胚层和内胚层细胞。
Mesenchymal stem cell ( MSC), originating from mesoblast, resides mainly in post-natal bone marrow as well as human umbilical cord blood, and coexists with hematopoietic stem cell ( HSC). 间充质干细胞(MSC)起源于中胚层,主要位于成体骨髓和人胎儿脐血,与造血干细胞共存。
There are some MSCs in adult marrow, it can turn into many mesoblast tissue by differentiation, including bone and cartilage tissue, tendon, muscle, fat and marrow stroma tissue. 成年人骨髓中存在一定数目的MSCS,能够通过分化形成多种中胚层组织,包括骨和软骨组织、肌鲢、肌肉、脂肪组织以及骨髓基质结缔.组织。