Public health experts worry that the worms will become resistant to this drug, praziquantel. 公共卫生专家担心,蠕虫将会对这种叫做吡喹酮的药物产生一种抗体。
Objective To observe the effect of different subclinical doses of praziquantel on the serum gut-associated cathodic antigen ( GACA) levels in the patients with chronic schistosomiasis. 目的观察不同亚治疗剂量吡喹酮对慢性血吸虫病患者血清血吸虫肠相关趋阴极抗原(GACA)水平的影响。
OBJECTIVE To prepare praziquantel implants and investigate the in vitro drug release. 目的制备胸腺五肽微球并对其体外释放进行考察。
Current schistosomiasis treatment relies largely on a drug called praziquantel ( PZQ). 目前,血吸虫病的治疗主要依靠吡喹酮(PZQ)药物。
Objective In order to study the tissue distribution of Praziquantel ( PZQ) and the pharmacokinetics after transdermal drug delivery. 目的研究透皮给药后吡喹酮在小鼠体内的组织分布及药代动力学。
Objective To explore the effect of combined therapy of artesunate and praziquantel for different infectiosity of Schistosoma japonicum in rabbits. 目的探讨青蒿琥酯和吡喹酮联用对日本血吸虫不同感染度家兔的治疗效果。
Until now, the main drug used to treat bilharzia has been praziquantel. 到目前为止,吡喹酮是治疗血吸虫病的主要药物。
Role of chemotherapy with praziquantel in schistosomiasis control 吡喹酮化疗在血吸虫病防治中的作用
However, a major limitation to schistosomiasis control is access to praziquantel. 吡喹酮的可得性是影响血吸虫病控制工作的一项重大限制因素。
Effect of high-dose praziquantel on clonorchiasis 大剂量吡喹酮治疗华支睾吸虫病疗效观察
Effect of quercetin combined with Praziquantel on expression of myocardial immediate early gene and transforming growth factor-β 1 in mice infected with Schistosomiasis japanica 槲皮素联合吡喹酮对小鼠日本血吸虫病心肌组织即早基因与转化生长因子β1表达的影响
The WHO strategy for schistosomiasis control focuses on reducing disease through periodic, targeted treatment with praziquantel. 世卫组织控制血吸虫病战略的重点是,使用吡喹酮进行定期的和有针对性的治疗,遏制血吸虫病。
Herbal retention enema combined with praziquantel in treatment of schistosomal colopathy 中药保留灌肠联合吡喹酮治疗血吸虫性结肠病
Conclusions Combined use of praziquantel and albendazole greatly improves the therapy of parenchymal neurocysticercosis with no obvious intracranial hypertension and shortens the treating time. 结论对于脑实质型脑囊虫病不伴颅内压升高者,吡喹酮与丙硫咪唑合用疗效明显提高。
Effect of Praziquantel on Circumoval Precipitin Test ( COPT) of Schistosoma Japonicum Eggs 吡喹酮对日本血吸虫卵环卵沉淀试验的影响
Praziquantel is the only available treatment against all forms of schistosomiasis. 吡喹酮是唯一可用于治疗各种类型血吸虫病的药物。
A Light and Electron Microscopical Observation of Liver Cell Damages after Administration of Therapeutic Dose of Praziquantel in Man 治疗剂量吡喹酮对人肝细胞影响的光学和电子显微镜观察
In this paper some host factors involved in the killing process of schistosomes induced by praziquantel were summarized. 本文对可能影响到吡喹酮杀虫作用的宿主因素进行综述。
On the contrary, fenbendazole and praziquantel appear to have no inhibitory effect on the A caninum egg development. 芬苯达唑和吡喹酮对虫卵发育无抑制作用。
In case of groups treated with flubendazole, fenbendazole or praziquantel, eggs showed cell division, or developed into ovum containing embryo or ovum containing a curling tapeworm. 芬苯达唑组虫卵发育成含胚卵。吡喹酮组之虫卵发育成含卷曲钩蚴。
Does praziquantel have immune regulatory effect? 吡喹酮是否具有免疫调节作用?
For cases of mixed infection of cestode or trematode praziquantel was used. 发现绦虫和吸虫感染者用吡喹酮驱治。
Objective To prepare solid lipid nanoparticles containing praziquantel ( PZQ-SLN) by ultrasonic technique, and investigate the main factors in the process of preparing PZQ-SLN. 目的采用超声分散法制备吡喹酮固体脂质纳米粒,并考察制备过程中的主要影响因素。
Effect of calcium channel blockers and actin depolymerizing/ stabilizing agents on the survival of Schistosoma japonicum treated with praziquantel in vitro 钙通道阻滞剂与肌动蛋白解聚/稳定剂对吡喹酮体外杀日本血吸虫作用的效应影响
Histopathologic examination also showed that liver egg granulomas in suppository rectal-praziquantel groups were less in number and smaller in size than those in single dose oral praziquantel groups. 研究证明,吡喹酮肛栓投药是治疗血吸虫病的又一有效途径。
Objective To observe the effect of praziquantel, mebendazole, tribendimidine, ivermectin, artemether and dihydroartemisinin against Amillifer agkistrodontis nymphs harbored in mice. 目的观察吡喹酮、甲苯达唑、三苯双脒、伊维菌素、蒿甲醚和双氢青蒿素对感染舌状虫小鼠的疗效。
OBJECTIVE: To prepare praziquantel aquogel suppositories and to establish its assay method. 目的:制备吡喹酮水凝胶栓剂,并建立其含量测定方法。
AIM: To observe the effect of praziquantel cyclosporin A combination on murine schistosomal hepatic fibrosis. 目的:观察环孢菌素A和吡喹酮联合应用对小鼠血吸虫性肝纤维化的影响。
Studies confirm that schistosoma mansoni can produce drugresistance to praziquantel in laboratory. 实验室研究已经证实了曼氏血吸虫在吡喹酮药物压力下可产生抗药性。