Ca~ ( 2+) Signaling Pathways Associated with the Invasion of Streptococcus pneumoniae to Type ⅱ Pneumocytes 钙信号转导途径介导肺炎链球菌侵袭人肺Ⅱ型上皮细胞
The rat type ⅱ pneumocytes were isolated, cultured and then exposed to cigarette smoke particulate extract or/ and β carotene for 24 hrs. Cell activity was detected with MTT assay. [方法]建立大鼠肺Ⅱ型细胞体外培养模型,加入β胡萝卜素或/和香烟烟气颗粒物用MTT比色法检测细胞活性。
A study of the expression of CD_ ( 44) in pneumocytes in pulmonary sarcoidosis 肺结节病肺泡上皮细胞CD(44)表达的观察
Type ⅱ pneumocytes filamentous actin rearrangements induced by Streptococcus pneumoniae in vitro 肺炎链球菌在体外触发人肺Ⅱ型上皮细胞F-actin细胞骨架重排
Alveolar type II cells are the stem cells of alveolar epithelium, they are multifunctional pneumocytes and play a important role in lung fluid transport. 肺泡Ⅱ型细胞是肺泡上皮的干细胞,是一种多功能肺细胞,在肺水转运中起着非常重要的作用。
To study the effect of β carotene on cultured rat pneumocytes exposed to extract of particulates of cigarette smoke. [目的]研究β胡萝卜素对香烟烟气颗粒物致肺细胞毒性的交互作用。
The pathological changes were diffuse pulmonary interstitial inflammation and alveolar damages with apoptosis and desquamation of pneumocytes in alveolar spaces, hyaline-membrane formation, wider alveolar walls and predominant lymphocyte and mononuclear inflammatory infiltrates. 结果:肺部病变主要表现为弥散性肺间质炎症及肺泡损伤,肺泡上皮细胞凋亡脱落及肺透明膜形成,肺间隔明显增宽,以淋巴细胞和单核细胞为主的炎细胞浸润。
Part ⅱ. The lamellar bodies of Type II pneumocytes were evacuated rapidly. Ⅱ型上皮细胞板层体急性排空。
The evacuation of substance from lamellar bodies in the type II pneumocytes can be seen as a characteristic pathological change caused by ARDS. Such lamellar body alteration in type II pneumocytes perhaps provides an important basis for the judgement of ARDS attack. 肺泡II型细胞胞质内板层小体排空为ARDS的特征性病理变化,肺泡II型细胞板层小体排空或许可以作为判断ARDS的重要依据。
Results: Obvious apoptosis of pneumocytes occurred early after ( 30 min) ischemia reperfusion lung injury, with the peak on 2 h after reperfusion, and there were no significant differences 12 h after reperfusion compared with control group. 结果:在肺缺血再灌注后早期(30min)发生明显的肺细胞凋亡,凋亡细胞数峰值位于再灌注后2h,再灌注后12h凋亡细胞数与对照组无显著差别;
Combination ⅱ. ( 3) pneumocytes were hyperplastic; 肺泡Ⅱ型上皮细胞增生。
Changes and Mechanisms in Gap-Junction Permeability Mediated by Connexin 43 in Silica-induced Pneumocytes 二氧化硅诱导肺细胞间隙连接功能下调及其分子机制的研究
Mesenteric Venous Thrombosis ( 3) pneumocytes were hyperplastic; 肠系膜静脉血栓形成(3)肺泡Ⅱ型上皮细胞增生。
To investigate the mechanism of oxidative stress on rat type ⅱ pneumocytes induced by the air pollution particle extracts of the railway transport station of chemical dangerous goods ( RTSCDG). [目的]探讨铁路危险品货运站空气污染颗粒提取物诱导大鼠肺细胞氧化应激损伤作用的机制。
Investigating on the relationship between F-actin rearrangements of type ⅱ pneumocytes induced by Streptococcus pneumoniae and TPK signal transduction in vitro 肺炎链球菌触发人肺Ⅱ型上皮细胞F-actin细胞骨架重排与TPK信号转导的相关性研究
Interaction of Beta-Carotene on Rat Pneumocytes Exposed to Cigarette Smoking Particle Extracts β-胡萝卜素与香烟烟气颗粒物对体外大鼠肺细胞毒性的交互作用
Results Compared to blank control group, Sp1 protein expression was increased in type ⅱ pneumocytes and peaked at the 7~ 14 th day in the silica-induced group; 结果大鼠矽肺模型中,SiO2刺激组与空白对照组相比,Ⅱ型肺泡细胞中核转录因子Sp1蛋白表达上调,于第7~14天达高峰;
Objective To explore the effects of bilirubin on expression of laminin ( Ln) and epidermal growth factor ( EGF) in lung tissue and in type ⅱ pneumocytes ( AT ⅱ) in smoking rats. 目的观察胆红素干预对肺气肿大鼠模型肺组织和肺泡Ⅱ型上皮细胞(ATⅡ)层黏连蛋白(Ln)及表皮生长因子(EGF)表达的影响。
Mechanism of Oxidative Stress Induced by Particulates in the Air Pollution of the Railway Transport Station of Chemical Dangerous Goods in Rat Pneumocytes 铁路危险品货运站空气颗粒物诱导肺细胞氧化应激损伤
Objective To investigate thyroid transcription factor-1 ( TTF-1) expression in normal human adult type ⅱ alveolar epithelial cells, embryonic pneumocytes, lung carcinoma cells and lymph node metastases of lung cancer. 目的揭示甲状腺转录因子-1(TTF-1)蛋白在正常成人肺泡Ⅱ型上皮细胞、人胚胎肺泡上皮细胞、肺癌原发灶及淋巴结转移灶中的表达特点及规律。
Objective To assess the efficacy of prenatal administration of epidermal growth factor ( EGF) on pulmonary hypoplasia in the Nitrofen induced congenital diaphragmatic hernia ( CDH) rat models and the effect on type ⅱ pneumocytes. 目的探讨上皮生长因子(EGF)对先天性膈疝(CDH)模型肺发育不良的影响,尤其是对Ⅱ型细胞的影响。
Results The number TTF-1 positive units ( PU) was smaller in the nuclei of embryonic pneumocytes than in those of normal adult type ⅱ alveolar epithelial cells ( P < 0.001). 结果胚胎肺泡上皮细胞核TTF-1阳性单位(PU)值小于正常成人肺泡Ⅱ型上皮细胞核TTF-1的PU值(P<0.001);
Immunohistochemistry: TGF-β 1 could be seen in the cytoplasm of bronchial epithelial cells, type ⅱ pneumocytes, vascular endothelium cells, alveolar macrophages and myofibroblasts. 免疫组织化学显示:肺组织中TGF-β1主要分布于肺泡上皮细胞、支气管上皮细胞、血管内皮细胞、巨噬细胞和肺成纤维细胞的胞浆。