nucleolin
英
美
n. 核仁素
双语例句
- Experiment on Relationship between Nucleolin and Drug-Sensitivity of Human Osteosarcoma Cell
核仁素与人骨肉瘤细胞化疗药物敏感性关系的实验研究 - Objective: To establish H9C2 cell line that can stably express the nucleolin, which can provide a cell line with which we can analyze the function of nucleolin in apoptosis of cardiomyocytes.
目的：建立稳定表达核仁素的H9C2大鼠心肌细胞株，为进一步研究核仁素在心肌细胞凋亡中的作用提供细胞模型。 - Effect of nucleolin down-regulation on the proliferation and apoptosis in C_2 C_ ( 12) cells
核仁素表达下调对C2C（12）细胞增殖与凋亡的影响 - Multiple snoRNAs Encoded in the Introns of Mammal Nucleolin Gene
哺乳动物核仁蛋白基因编码多个内含子snoRNA - Further co-localization with C23/ nucleolin antibody demonstrated that X2 protein localized in the nucleolus of transfected cells in the absence of any other viral proteins and displayed dotted nucleolus signal pattern.
进一步与核仁蛋白C23共定位，发现X2蛋白定位于核仁，且在不同细胞中，X2蛋白的定位状态表现一致。 - Cellular uptake experiments show that Apt-NPs-PTX could target to nucleolin largely expressed human breast cancer cell line ( MCF-7). but there is no detectable targeting to normal cells.
细胞摄取实验表明，Apt-NPs-PTX能够靶向核仁素大量表达的人乳腺癌细胞系（MCF-7），而对正常细胞却无明显的靶向作用。 - Nucleolin is a multifunctional RNA-binding protein, and is closely associated with apoptosis.
核仁素是一种多功能的RNA结合蛋白，与细胞凋亡密切相关。 - Nucleolin is associated with unmethylated rDNA genes and ChIP-seq experiments identified a strong enrichment of nucleolin in the promoter and coding regions of rDNA.
核仁素结合未甲基化的rDNA，ChIP-seq实验表明核仁素在rDNA的启动子和转录区有强烈的富集。 - After myocardial I/ R injury, nucleolin transgenic mice showed less caspase-3 activity, less serum creatine kinase activity and higher left ventricular pressure maximum rise rate (+ LV Max dP/ dt) than those in wild type mice.
与野生型小鼠相比，核仁素转基因小鼠心肌缺血-再灌注损伤后心肌caspase-3活性降低，血清肌酸激酶活性降低，左室压最大上升速率（+LVMaxdP/dt）升高。 - [ Conclusion] Nucleolin protects myocardium against ischemia-reperfusion ( I/ R) injury in mice.
[结论]核仁素在整体动物水平能减轻心肌缺血-再灌注损伤。