It was indicated that n-Propylamine dropropizine had greater effect on cough than LD, while the other compounds with Amino groups as substitutes had comparable activity with LD as antitussive. 初步药理实验表明,正丙胺羟丙哌嗪镇咳活性明显优于左羟丙哌嗪(LD),而其他胺基取代的目标化合物镇咳活性与左羟丙哌嗪(LD)相比无明显改变。