Study of pharmacokinetics and LC-MS/ MS method of blood concentration of methyclothiazide LC-MS/MS法测定甲氯噻嗪血浓度及药动学研究
The concentration of methyclothiazide in blood plasma was measured by an validated LC-MS/ MS method and were assessed with non-compartment model to obtain the pharmacokinetic parameters. 方法采用LC-MS/MS法测定血浆中甲氯噻嗪的浓度并用非房室模型计算药动学参数。