Study on pseudomonas aeruginosa with metallo-β-lactamase and its drug resistance in newborn infection RESPIRATORY SYNCYTIAL VIRUS INFECTION ENHANCES AIRWAY HYPERRESPONSIVENESS IN GUINEA PIGS AND THE UNDERLINED MECHANISM PAE产金属β-内酰胺酶分离株与新生儿感染耐药性呼吸道合胞病毒感染促进豚鼠产生气道高反应性及其机制研究
Detection of Metallo-β-lactamases Produced by Multi-drug Resistant Acinetobacter baumannii ICU多药耐药鲍氏不动杆菌金属β-内酰胺酶检测
Computer simulation analysis on the IMP metallo-β-lactamase active center IMP型金属β-内酰胺酶活性中心的计算机模拟分析
Metallo-β-lactamase Produced by Carbapenem-resistant Pseudomonas aeruginosa Drug resistance Property of a disease-causing organism that allows it to withstand drug therapy. 耐碳青酶烯类抗菌药物铜绿假单胞菌金属酶研究抗药性:致病生物的属性,使其能够抵抗药物疗法。
Detection of Metallo-β-lactamase in Multi-resistant Pseudomonas aeruginosa 多药耐药铜绿假单胞菌产金属β-内酰胺酶的检测
Study of metallo-β-lactamase of Carbapenems-resistant Acinetobacter baumanii 耐碳青霉烯类鲍曼不动杆菌金属β-内酰胺酶的研究
Analysis of Antibiotic Resistance of Metallo-β-lactamase of Pseudomonas Aeruginosa in Clinical Isolates 临床分离产金属酶铜绿假单胞菌的耐药性分析
Study on the Genotypes of Metallo-β-lactamases in Pseudomonas Aeruginosa 产金属酶的铜绿假单胞菌基因分型的研究
Antimicrobial Resistance of Pseudomonas aeruginosa and Detection of Its Metallo-β-lactamases 铜绿假单胞菌的耐药性分析与金属β-内酰胺酶检测
Double-Disk Synergy Test in Screening Metallo-β-Lactamase 双纸片增效试验筛查金属β-内酰胺酶
Objective: To study genetypes of metallo-β-lactamase in pseudomonas aeruginosa and analyze the transfer mechanism of resistance genes. 目的:研究铜绿假单胞菌中金属β-内酰胺酶的的基因型及基因的转移机制,为监控产酶菌株的流行及指导临床合理选择抗生素提供依据。
Metallo-β-lactamase-producing isolates were screened by double-disk synergy test and double-disk enhancement test; 双纸片协同试验和增效试验筛选金属β-内酰胺酶;
The rate of producing Metallo-β-lactamase was 31.8% in 22 imipenem-ceftazidime resistance PA isolates. 22株耐头孢他啶和亚胺培南铜绿假单胞菌的产金属β-内酰胺酶率为31.8%。
Objective: To establish a convenient double-disk synergy test for screening pseudomonas aeruginosa producing metallo-β-lactamase. 目的:建立简便的双纸片增效试验,筛查产金属β-内酰胺酶的铜绿假单胞菌。
Synthesis, Architectures, and Applications of Metallo-supramolecular Polymers 金属-超分子聚合物的合成,结构与应用
The metallo-β-lactamase was detected by the double disk synergy method. 采用双纸片协同法检测金属β-内酰胺酶。
Among 71 strains of Pseudomonas aeruginosa resistant to imipenem, 18.3% produced metallo-β-lactamases. 71株耐亚胺培南的铜绿假单胞菌中有18.3%产金属β-内酰胺酶。
All 8 strains of metallo-β-lactamases-producing bacteria were resistant to β-lactams antibiotics and antibiotics containing β-lactamases inhibitors or Imipenem. Only was it rather sensitive to Azlocillin, Amikacin and Ciprofloxacin. 8株产金属酶细菌对β内酰胺类抗生素、含β内酰胺酶抑制剂的复合抗生素及亚胺培南全部耐药,仅对氨曲南、阿米卡星及环丙沙星较敏感。
Methods: Metallo-β-lactamase positive strains were screened from imipenem-resistant or ceftazidime-resistant pseudomonas aeruginosa isolates by E test strips of imipenem with and without EDTA. PCR was used to amplify the resistant genes of imp 、 vim 、 spm and gim. 方法:E-test筛选对亚胺培南或头孢他啶耐药的铜绿假单胞菌中的产金属β-内酰胺酶菌株,PCR扩增耐药基因imp、vim、spm和gim。
Two strains produced VIM-2 metallo-β-lactamases. 29株菌中有2株产VIM-2金属β内酰胺酶(6.9%)。
Methods Screening Acquired Metallo-β-lactamase s 获得性金属β-内酰胺酶初筛方法的研究
Detection of IMP Gene of Metallo-β-Lactamases In Imipenem-resistant Bacteria 耐亚胺培南细菌金属β-内酰胺酶IMP基因的检测
Conclusion: The method was established for the expression, purification and characterization of metallo-β-lactamases ( IMP-1), which can be applicable to other metallo-β-lactamases. 结论:本文建立了金属β-内酰胺酶IMP-1的表达、纯化、鉴定方法,该法可用于其它的金属β-内酰胺酶的表达和纯化。
Conclusions: Production of metallo-β-lactamase is one of the resistance mechanisms of Pseudomonas aeruginosa to carbapenems. 结论:产生金属β内酰胺酶是铜绿假单胞菌对碳青霉烯类药物耐药的机制之一。
METHODS PCR method was used to detect and analyze P.aeruginosa imipenem-resistance associated IMP gene and VIM gene of metallo-β-lactamases and outer membrane protein D2 ( OprD_2) gene. 方法用PCR法对铜绿假单胞菌亚胺培南耐药相关的金属β-内酰胺酶IMP、VIM基因和外膜蛋白OprD2基因等3种主要耐药基因进行了检测与分析。
Metallo-β-lactamase& a new challenge for anti-infective therapy 金属β-内酰胺酶&抗感染治疗面临的新挑战
Methods: The double-disk synergy test with three different substrates was used to detect metallo-β-lactamase. 方法:3组不同底物的双纸片增效试验检测金属β-内酰胺酶,比较其结果。
Objective: To establish the method for the expression, purification and characterization of metallo-β-lactamases ( IMP-1) and to explore the influence of experimental conditions on its separation and purification. 目的:建立金属β-内酰胺酶IMP-1的表达,纯化和鉴定方法,并探讨实验条件对分离纯化的影响。
Sequence analysis, prokaryotic expression and purification of VIM-2 metallo-β-lactamase VIM-2型金属β内酰胺酶的序列分析、原核表达及纯化