Preparation and in vitro release of mesna polylactic acid microspheres 美司钠聚乳酸微球的制备及体外释放
The home-made mesna ( 20-80mg · kg-1) had protective effects for the animal model. The visceral coefficient of bladder and the optical density of homogenate were decreased by home-made mesna, mesna reduced also the hemorrhagic percentage of bladder mucosa. 国产麦斯纳(20~80mg·kg-1)对这种动物模型有保护作用,使膀胱脏器系数和组织匀浆吸光度减少,膀胱粘膜出血百分率下降。
Mesna 0.4g iv at 0,4, 8 hour after the administration of IFO on d 1-3; Mesna0.4g,静注,于IFO静滴后0、4、8小时各一次,d1-3;
The results indicated that domestic mesna can be acted as an antidote for hemorrhagic cystitis induced by CTX. 结果提示国产麦斯纳可以作为环磷酰胺引起出血性膀胱炎的解毒剂。