Pharmacokinetics of memantine hydrochloride capsule in Chinese healthy volunteers HPLC assaying of aconitine in Xiaojin capsules 盐酸美金刚胶囊人体药代动力学研究HPLC测定小金胶囊中乌头碱的含量
The researchers also found that memantine was able to dampen brain activity in some affected areas and reduce pain accordingly. 研究人员也发现美金刚胺能够抑制脑中受侵袭部位的活动从而减少疼痛。
HPLC-ELSD method was established for determination of memantine hydrochloride in memantinetablets. 建立了HPLC-ELSD测定美金刚胺片中盐酸美金刚胺的含量。
Determination of Memantine hydrochloride in rats 'plasma by precolumn derivation-HPLC 柱前衍生化HPLC测定大鼠血浆中的盐酸美金刚胺
Influence of memantine hydrochloride on short-term cognition and EEG power spectrum in patients with mild to moderate Alzheimer's disease 盐酸美金刚对轻、中度阿尔茨海默病患者短期认知功能及脑电功率谱的影响
Clinical efficacy and safety of memantine in the treatment of Alzheimer's disease 盐酸美金刚治疗阿尔茨海默病的疗效观察
The pathologic changes and mortality rate of neonatal rats were positively correlated with the dosage of memantine. 新生大鼠的病理变化程度及死亡率与美金胺的剂量呈正相关。
Methods The therapeutic schedules of Memantine and atropine were arranged according to the L9 ( 34) orthogonal test table. The survival time, the loss of righting reflex and the latency of onset of muscle fasciculations were observed. 方法根据正交实验设计原理,选用L9(34)正交表,以肌束震颤出现时间、翻正反射消失时间和存活时间为指标,分别测试美金刚和/或阿托品对敌敌畏染毒小鼠的治疗效果。
Memantine hydrochloride is an amantadine derivative. It is a moderate affinity, non-competitive N-methyl-D-aspartate ( NMDA) antagonist. 盐酸美金胺是盐酸金刚烷胺衍生物,它是具有中等亲和力的非竞争性的N-甲基-D-天门冬氨酸(NMDA)受体拮抗剂。
Conclusion The results showed that, the combined treatment of Memantine and atropine could effectively antagonize the acute toxicity of Dichlorvos, and improve the intoxicated signs such as the intensity of muscle fasciculations. 结论美金刚和阿托品联合使用对敌敌畏中毒有很好的协同治疗作用,可明显改善肌束震颤症状。
A 24-week open-label extension study of memantine in moderate to severe alzheimer disease 一项为期24周的美金刚治疗中度至重度阿尔茨海默病的开放标记延伸研究
Behavioral effects of memantine in Alzheimer disease patients receiving donepezil treatment 美金刚对接受多奈哌齐治疗阿尔茨海默病患者的行为效应
Toxic reaction of memantine in neonatal rats after repetitive administration 美金胺重复用药对新生大鼠的毒性反应
Conclusions Administering memantine immediately after HI can markedly increase the abilities of spatial discrimination, learning and memory and improve the long-term prognosis in rats with HI brain damage. 结论新生大鼠在脑缺氧缺血后即刻使用美金胺可显著增强其空间辨识和学习记忆功能,改善其长期预后。
Epidemiology study on characteristics of acute intoxication in emergency department and analysis on influencing factors of poisoned death 美金刚(Memantine)对敌敌畏中毒小鼠的实验治疗研究急诊中毒特点及中毒死亡影响因素分析
AIM: N-methyl-D-aspartate receptor ionic channel antagonist, memantine has significantly cerebral protective effects on hypoxic/ ischemic rats. To observe the side effects of repetitive application of memantine at big dosage in SD neonatal rats. 目的N-甲基-D-天冬氨酸受体离子通道拮抗剂美金胺对缺氧缺血具有明显的脑保护效果,观察重复应用大剂量美金胺对SD新生大鼠可能造成的不良影响。
Objective Animal trials have demonstrated that memantine has neuroprotective effects on hypoxic-ischemic ( HI) brain damage. 目的动物实验已证明美金胺对缺氧缺血脑损伤具有神经保护作用,但是美金胺治疗能否改善脑缺氧缺血大鼠的长期预后,目前尚无有关研究资料。
The memantine was well tolerated in neonatal rats. 新生大鼠对美金胺有较好的耐受性。