The apoptosis was characterized by chromatin concentration and margination, in half-moon, loop, and irregular shapes, and apoptotic body formation, and DNA ladder formation by gel electrophoresis. 凋亡的细胞表现为核染色质浓缩、边移,呈半月型、环状或不规则状,凋亡小体形成,电泳下见DNA梯状图谱。
With electron microscopy, great changes of cell apoptosis were observed, including microvilli disappearance or reduction, cell shrinkage, chromatin condensation or margination and the presence of "apoptosis bodies". 扫描和透射电镜观察可见各实验组细胞表面微绒毛明显减少或消失、胞膜发泡、细胞固缩和核染色质浓缩边集,并出现凋亡小体,热疗+工SDN组的凋亡细胞数量更多。
The results are as follows: ( 1) Cold induced apoptosis in yeast cells, moreover, yeast cells display representive features such as chromatin condensation, DNA fragmentation and chromatin margination. 研究结果如下:①冷诱导酵母细胞发生凋亡,并呈现凋亡的典型特征如细胞核染色质的凝聚、断裂、边缘化;
Chromatin margination and apoptotic bodies were found in RB. TUNEL positive labeling cells especially located in tumor regress area. 结果光镜下凋亡细胞主要位于RB退化区,电镜下可见染色质边集和凋亡小体等凋亡特征;TUNEL显示阳性标识主要位于RB退化区及死亡区。
The morphological changes of apoptosis including chromatin condensation and margination, appearance of vacuoles on the cytomembrane, and the formation of apoptotic bodies. 凋亡细胞的形态学改变是细胞体积缩小,细胞器结构正常,染色质初期浓集成团,聚集于核膜的周边,随后出现染色质凝聚,核碎裂以及凋亡小体形成等现象。
The change of nucleus were significant margination of chromatin 24 h after SE. SE后24h细胞核染色质明显边聚。
Results: The grub extract significantly inhibited the proliferation of gastric cancer cells in vitro, morphologic changes of apoptosis with chromatin margination, karyopyknosis, karyorrhexis, apoptotic body were found by the light scope. 结果:光镜结果表明,蛴螬(终浓度为4mg/ml)作用于MGC-803胃癌细胞24h后,可见胞核固缩、胞核碎裂、凋亡小体形成等凋亡形态学变化;
Results: Mitochondria swelling, endoplasmic reticulum swelling and chromatin margination were the main pathological manifestations in neurons, neurogliocytes and nerve fiber cells in the cerebrum, cerebellum and brain stem. 结果:大脑、小脑及脑干神经细胞、胶质细胞及神经纤维细胞内线粒体肿胀及染色质边集、内质网肿胀是其主要病理变化。
Results Characteristic morphologic changes of apoptotic cells were observed under transmission electron microscope with chromatin condensation and margination as well as formation of apoptotic bodies. 结果透射电镜观察发现凋亡细胞典型的形态学变化&核染色质凝集边集,凋亡小体形成等。
The combined effects of quercetin and octreotide on cell ultrastructure of human breast carcinoma cell lines MCF-7 and MDA-MB-231: ( 1) Swelling mitochondria and vacuolation in cytoplasm and nucleolar margination were frequently seen in MCF-7 cells. 槲皮素与奥曲肽联用对MCF-7和MDA-MB-231细胞超微结构的影响:(1)两药联用于MCF-7,胞质内出现较多的局部空化现象,多数线粒体嵴内间隙肿胀,核仁边集。
Mitochondria swelling and chromatin margination were main ultrastructural changes of neurocyte damage. 脑室内出血后脑细胞受损的超微病理改变主要是线粒体肿胀及染色质边集;
The changes of ultrastructure in model group included heterochromatin margination in some myocyte and more collagen fibers in myocardium. 电镜下见模型组部分心肌细胞核内染色质边聚现象,间质胶原纤维增多。
Results Neutrophil margination, superficial necrosis of the villi, sloughing of epithelium, and complete absence of some villi in ileum were observed in Group A. 结果A组回肠黏膜绒毛上皮表浅坏死,伴中性粒细胞浸润以及上皮脱落;
In the androgen group, ultramicrostructure was harmed less severely than that in the castrated group, with clear nuclear membrane, insignificant margination of the chromatin, no obvious change of the mitochondria shape and less lipofuscin. Conclusions: 1. 雄激素组超微结构损伤较去势组减轻,神经元核膜较清晰,核内染色质边集不明显,线粒体形态未见明显异常,脂褐素沉积减少。
HE staining showed similar changes with view which observed under the inverted microscope, it also showed chromatin margination, cell shrinkage and apoptotic cells. HE染色、应用光学显微镜我们观察到了与倒置显微镜相同的改变,并可见染色质边集,细胞固缩,凋亡小体等典型的凋亡形态学改变。
The results in middle intensity and high intensity groups showed that mitochondrial swelling, mild edema around capillaries, chromatin condensation and margination, and endothelial cell vacuolization could be observed in neurons and glial cells. 中辐射组和高辐射组可见组织中神经元、神经胶质细胞线粒体肿胀,毛细血管周围轻微水肿,核染色质浓缩、边集,血管内皮细胞有空泡形成。
Low-dose group: loosen of mesothelial cells, discontinuous distribution of cell surface, obvious decrease of microvilli, swelling of cell organ, margination and solidification of nucleus chromatin, disappear of tight junction of neighbour mesothelial cells were observed. 低剂量组:间皮细胞疏松,细胞表面不连续,微绒毛明显减少,细胞器肿胀,胞核染色质边集、凝固,相邻间皮细胞紧密连接消失。
Electron microscope examination showed that DEX and A β could induce the chromatin margination phenomenon, cytoplasm vacuoles, mitochondrial swelling and ridges disappear, and reduce the number of ribosomes in hippocampal neurons. 电镜检查结果显示,DEX和Aβ协同作用大鼠脑组织海马神经元染色质有边集现象,胞浆内有大量的空泡形成,线粒体肿胀明显,脊消失,核糖体数量明显减少。