Effects of Wang-Bi tablet on cytokines and leukomonocyte subgroup in rats with adjuvant-induced arthritis 尪痹片对佐剂性关节炎大鼠T细胞亚群和细胞因子变化的影响
Long-time violent exercise reduced the number of peripheral blood leucocyte, especially in leukomonocyte. Proportion of CD4+ T cell reduced or the down regulation of CD4+/ CD8+ ratio could inhibit the function, but the function of phagocytic cells increased. 长时间剧烈运动减少外周血白细胞,尤以淋巴细胞为甚,CD4+T细胞的比例下降,或CD4+/CD8+比值下调,并抑制其功能,但吞噬细胞功能可增强。
After the termination of experiment, lymphocyte proliferation were assayed. Levels of IFN-γ and IL-6 in the supernatants of leukomonocyte culture were measured by enzyme-linked immunosorbent assay. 3H-TdR掺入法检测淋巴细胞增殖反应,酶联免疫吸附实验检测淋巴细胞培养液上清中干扰素(IFN)-γ、白细胞介素(IL)-6的含量。
Thoracic gland and spleen were obtained by dissection to inspect the changes in cortical thickness ( CT) of spleen, thymic lymphocyte ( TL), size of splenic corpuscle and the leukomonocyte number of spleen. 解剖取胸腺和脾脏,检测胸腺皮质厚度、胸腺淋巴细胞数、脾小结大小、脾脏淋巴细胞数病理学指标的变化。
The bone density in patients with PMO of liver and kidney deficiency was significantly increased, and the levels of T leukomonocyte subgroup CD3, CD4, the ratio of CD4/ CD8 and levels of serum immune IgG, IgM were greatly enhanced in patients. 肝肾不足型绝经后骨质疏松症患者的骨密度值显著提高,患者T淋巴细胞亚群CD3,CD4水平、CD4/CD8比值以及血清免疫学IgG,IgM水平明显提高。
There is growing reports to show that, in addition to DRG, many of other type of cells such as leukomonocyte and endothelial cells are also able to synthesize CGRP, which exerts multiple functions through autocrine or paracrine secretion. 新近研究发现,非神经组织细胞如淋巴细胞、内皮细胞也能合成CGRP,通过自分泌或旁分泌而发挥作用。