leukemogenesis
英
美
网络 骨髓性白血病的致癌
双语例句
- The Basic and Clinical Study of Notch Signaling in the Acute Leukemogenesis
Notch信号通路与急性白血病发病的基础和临床研究 - Objective To investigate the changes of telomerase activity and its related genes expression in leukemia cells and their roles in leukemogenesis.
目的研究端粒酶活性和相关基因表达在白血病患者中的变化及其在白血病发病机制中的意义。 - The aim of the study was to evaluate the role of the HCP gene in leukemogenesis.
本研究旨在评价HCP基因突变在急性白血病发病中的作用。 - The stem cell leukemia ( SCL) gene is a new oncogene related with leukemogenesis.
干细胞白血病（CL）因是新发现的与白血病发生有关的癌基因。 - Role of PML-RAR α fusion gene in promyelocytic leukemogenesis
PML-RARα基因在早幼粒细胞性白血病发病中的作用研究 - Our results argue that LOH is an important event in CML and the inactivation or loss of a possible tumor sup-pressor gene may be involved in the leukemogenesis of CML.
研究结果提示，LOH是CML中的一个重要事件，可能涉及在CML发生中abl基因座位附近的TSG的失活或丢失。 - Objective: To elucidate a role for the Wilms tumor gene ( WT1) in leukemogenesis.
研究Wilms瘤基因在白血病发病中的作用机制。 - Constitutive activation of JAK/ STAT signaling pathway in leukemogenesis
白血病形成中JAK/STAT信号通路的持续激活 - Detection of CBF β/ MYH11 fusion transcripts and study of the mechanism of leukemogenesis of CBF β/ SMHHC fusion protein
CBFβ/MYH11融合基因转录本检测及其致白血病机制的研究 - Epigenetic modification, which involve DNA methylation, RNA-associated silencing and histone modification, is implicated in cell proliferation, differentiation, survival, apoptosis and malignant transformation. Some leukemogenesis has been shown to be aberrance of epigenetic modification.
表观遗传修饰（epigeneticmodification），如DNA甲基化、组蛋白乙酰化和甲基化、RNA相关性沉默与细胞生长、分化、凋亡、转化及肿瘤进展相关基因的转录密切相关。 - These data suggested that there is probably abnormal retinoic acid metabolism in leukocytes from leukemic patients, and this abnormality may be responsible for the leukemogenesis.
提示白血病患者的白细胞内维甲酸代谢可能存在异常，并可能与白血病的发病有关。 - Recently it was found that WT1 was expressed in hematopoietic tissue, and played a role in leukemogenesis, and the development and prognosis of leukemia.
近年来发现它在造血组织中也有表达，并与白血病的发生、发展及预后有关.由于WT1在白血病中的表达有一定规律性，故可能成为微小残留白血病的检测标志。 - This study was aimed to analyze the different proteomes between human acute leukemia ( AL) cells and normal white blood cells by proteomic technology in order to lay the basis for diagnosing AL and understanding the mechanism of leukemogenesis.
本研究利用蛋白质组学方法将急性白血病（acuteleukemia，AL）细胞与正常白细胞进行差异蛋白质组分析，为AL的分子诊断和白血病发生的分子机制研究奠定基础。 - Conclusion: IRF-1 gene may be an important suppressor gene in leukemogenesis. There may be deletion or partly deletion of IRF-1 gene in leukemia. It is value for treatment and diagnosis of leukemia.
结论：IRF1基因是影响白血病发病的一个重要的抑癌基因，在白血病可能存在缺失或部分失活的异常改变，对白血病的诊治有参考价值。 - There are two categories of mutations or gene rearrangements which play important role in molecular mechanisms of leukemogenesis.
关于白血病分子发病机制研究目前认为有两类突变或基因重排起重要作用。 - The results also showed that the miR-30a in CML is low expression and plays a tumor inhibitory effect, suggesting that low expression of miR-30a is related with chronic myeloid leukemogenesis, and the specific mechanism needs further study.
结果也表明miR-30a在慢粒中低表达且起到肿瘤抑制作用，推测1niR-30a的低表达和慢粒的发生机制有关，具体机制尚需进一步研究。 - The new study shows that VPA can remit leukemogenesis mediated by AML1/ ETO fusion gene through breaking abnormal function of HDAC.
研究发现VPA通过破坏异常的HDAC功能而有效地缓解AML1/ETO融合基因介导的白血病生成。