Simultaneous determination of the contents of lamotrigine and oxcarbazepine in human plasma by RP-HPLC method 用RP-HPLC法同时测定拉莫三嗪和奥卡西平的血药浓度
Effects of Lamotrigine on Neurogenesis in the Dentate Gyrus of Adult Rats 拉莫三嗪对成年癫癎大鼠齿状回神经发生的影响
Study on treatment of central post-stroke pain using lamotrigine Central mechanism of triptorelin therapeutic effects on female precocious puberty in rats 拉莫三嗪对脑卒中后中枢性疼痛的疗效研究曲普瑞林治疗真性性早熟的中枢机制
The article reviews the recent progress in research on the neuroprotective effect and its mechanism of lamotrigine in cerebral ischemia. 文章就近年来拉莫三嗪对脑缺血的神经保护作用及其机制的研究进展做了综述。
Severe exfoliative dermatitis and hepatic damage due to lamotrigine 拉莫三嗪致严重剥脱性皮炎及肝损害
Lamotrigine ( in both formulations) can also cause other types of allergic reactions or serious problems that may affect parts of the body such as the liver or blood cells. 拉莫三嗪(两种剂型)也会导致其他类型的过敏反应或严重问题。它们可能影响身体健康,比如肝或血细胞。
Methods: We collected the adverse reactions of new anticonvulsants, such as gabapentin, felbamate, lamotrigine, oxcarbazepine and tiagabine in body through literatures in home and abroad. 方法:查阅国内外文献,探讨了加巴喷丁、非氨酯、拉莫三嗪、奥卡西平、替加宾等新的抗癫痫药在各个系统的不良反应。
Effect of lamotrigine of different concentration on the survival rate and the expression of BDNF and p-CREB in the cultured hippocampus neuron 不同剂量拉莫三嗪对体外培养海马神经细胞存活及其BDNF和P-CREB表达的影响
The risk of developing a rash is higher if taking lamotrigine while also taking valproate or divalproex sodium or if taking a higher starting dose or increasing the dose faster than prescribed. 如果使用拉莫三嗪的同时使用了丙戊酸钠或双丙戊酸钠,或者采用了更高的起始剂量,或是增加剂量速度过快都有可能增加发生皮疹的风险。
However, no significant alterations were observed in patients on long-term lamotrigine monotherapy. 但是,长期的拉莫三嗪单一治疗的患者未发现明显改变。
Effect of lamotrigine on apoptosis in hippocampus of rats with chronically kindled epilepsy 拉莫三嗪对慢性致痫大鼠海马细胞凋亡的影响
Objective To study the antiepileptic effectiveness of Lamotrigine ( LTG) in different co-medication, and the relationship with dosage, serum concentration etc. 目的探讨拉莫三嗪(LTG)单药及不同配方治疗癫癎的有效性及与血药浓度等相关因素的关系。
HPLC method was established for the simultaneous determination of phenobarbital, lamotrigine, oxcarbazepine and monohydroxycarbazepine in human plasma. 建立了HPLC法同时测定人血浆中苯巴比妥、拉莫三嗪、奥卡西平及其代谢物单羟奥卡两平浓度。
Objective To investigate the neuroprotective effects of flunarizine ( FNZ) and lamotrigine ( LTG), and their combination on the hypoxic-ischemic brain damage in fetal rats. 目的研究氟桂利嗪(FNZ)、拉莫三嗪(LTG)及两药联合经孕鼠给药,对胎鼠宫内缺血缺氧性脑损害的保护作用。
Clinical efficacy of lamotrigine in patients with refractory epilepsy 拉莫三嗪治疗顽固性癫痫的临床观察
Gestation-induced changes in lamotrigine pharmacokinetics: A monotherapy study 妊娠诱发的拉莫三嗪药代动力学改变
Conclusion: lamotrigine had good efficacy in children with refractory partial epilepsy and may be a useful drug in the treatment of epilepsies in children. 结论:拉莫三嗪对儿童期难治性部分性癫痫有良好疗效,并可推广应用于其它类型的癫痫。
Neuroprotective Effects of Flunarizine and Lamotrigine on Hypoxic-ischemic Brain Damage in Fetal Rats 氟桂利嗪和拉莫三嗪对胎鼠缺血缺氧性脑损害的保护作用
Conclusion Combination therapy with low-dose Cortrosyn Depot, high-dose Vitamin B 6 and Lamotrigine was a safe and effective way in dealing with infantile spasms. 结论长效确杜先联合拉莫三嗪及维生素B6治疗婴儿痉挛,能迅速有效地控制其痉挛发作,且复发率低,副作用小,是治疗婴儿痉挛更为安全有效的方法。
Lamotrigine as Add-on Drug in the Management of Intractable Epilepsy 添加拉莫三嗪治疗难治性癫痫
To verify the curative effect and safety of lamotrigine ( LTG) for the treatment of childhood epilepsy, a open-label, add-on, self-control study was undertaken on 44 children with intractable epilepsy. 为验证拉莫三嗪治疗儿童癫痫的疗效和安全性,对44例儿童顽固性癫痫进行了开放性自身对照研究。
The efficacy of lamotrigine in children with refractory partial epilepsy 拉莫三嗪对难治性部分性癫痫的疗效观察
Effect of antiepileptic drug comedication on lamotrigine clearance 抗癫痫药物联合应用对拉莫三嗪清除率的影响
Objective To investigate the efficacy of lamotrigine combined with lithium carbonate in rapid cycling bipolar disorder. 目的探讨碳酸锂联用拉莫三嗪对双相情感障碍快速循环型的疗效。
Preventing disturbing migraine aura with lamotrigine: An open study 拉莫三嗪预防偏头痛先兆的开放性研究
Double-blind, Placebo-controlled Study of Lamotrigine in Primary Generalized Tonic-clonic Seizures 研究拉莫三嗪在原发性泛发性强直-阵挛发作中的作用
Self-control study of lamotrigine for the treatment of childhood epilepsy 拉莫三嗪治疗儿童癫痫的自身对照研究
Objective To study the effect and safety of small doses of Cortrosyn Depot combination with Vitamin B 6 and Lamotrigine in the treatment of infantile spasms. 目的探讨长效确杜先联合拉莫三嗪及维生素B6治疗婴儿痉挛的安全性。
Recent studies indicated that Lamotrigine ( LTG), as a new anti-epileptic drug, can improve cognition function of patients with epilepsy. 拉莫三嗪(LTG)作为一种新型抗癫癎药物,临床研究表明可以改善癫癎患者的认知功能。
Lamotrigine is a good choice in treating patients with epilepsy incorporate in mild and moderate depressive disorder. 因此,对于癫痫合并轻、中度抑郁障碍的患者,拉莫三嗪是一个很好的药物选择。