Objective To study the effects of temperature on calcium activated potassium channels ( KCa) in hypothalamic neurons of new born SD rats. 目的研究新生SD乳鼠下丘脑神经元钙激活钾通道的温度敏感性。
Expressions and changes of KCa channel in detrusor in rats with detrusor instability 钙离子激动钾通道在大鼠逼尿肌不稳定膀胱中的表达及变化
Objective to investigate the therapeutic effect of dehydroepiandrosterone ( DHEA), an Ca2+-activated K+ channel ( Kca) opener, and nifedipine an calcium channel blocker, on chronic hypoxic pulmonary hypertension in rats. 目的对慢性缺氧3周大鼠静脉注射钾通道开放剂脱氢表雄甾酮(DHEA)和钙通道阻断剂nifedipine,以对照研究它们对大鼠慢性低氧性肺动脉高压的治疗作用。
Objective: Effects of Mg2+ on Ca2+-activated K+ channel ( Kca) in porcine coronary arterial smooth muscle cells were studied to reveal the electrophysiological mechanism about the effects of mg2+ on the dilatation of blood vessel. 目的:研究Mg2+对猪冠脉平滑肌细胞钙激活钾通道的作用,以揭示Mg2+扩血管作用的电生理机制。
Objective To study the modulation alterations of calcium activated potassium channel ( Kca) and calcium activated chloride channels ( Clca) on detrusor instability ( DI) and their roles in DI. 目的研究钙激活钾/氯通道对逼尿肌不稳定的调节作用的变化,探讨其在逼尿肌不稳定(detrusorinstability,DI)发生中的作用。
Objective To study the modulation of calcium activated potassium channels ( Kca) and calcium activated chloride channels ( Clca) on the contraction of detrusor strips, and to investigate the role of these channels play in DI. 目的探讨钙激活钾通道和氯通道对逼尿肌条收缩的调节在逼尿肌不稳定发生中的作用。
Objective: To study the effect of PGE 1 on calcium-activated potassium channels ( K Ca) from human mesentery artery smooth muscle cell ( SMC). 目的:探讨前列腺素E1(PGE1)对人肠系膜动脉平滑肌细胞钙激活钾通道(KCa)活动的影响。
Method: Wistar rats were used, and the action of breviscapine on K_ ( Ca) was studied in rat aortic smooth muscle using the Patch-clamp technique. 方法:采用Wistar大鼠20只,应用膜片钳技术,研究灯盏花素对大鼠主动脉平滑肌KCa的作用。
It indicated that H 2O 2 induced different activities on K Ca channel with different tissues. H2O2对K+通道的作用表明,H2O2介导的KCa通道活性改变因组织类别的不同而亦有差异。
Aim: To observe the effects of Ca~ ( 2+)-activated K~+ channel of primary cultured fetal SD rat cortex neurons in the veratridine triggered neuronal damage. 目的:观察新生SD大鼠原代培养皮层神经元的钙激活钾通道(Kca)在黎芦碱致神经元损伤模型上的激活、抑制效应。
Results: Nitric oxide was found to increase the open probability of the channels directly or through increasing cGMP, which resulted from both the prolongation of open period and increase of open frequency. 结果:NO可直接或通过升高cGMP来提高KCa通道的开放概率(Po),这种增强作用是因为通道开放时间延长及开放频率增加。
Objective To investigate the influence of glycodeoxycholate ( GDC) on open probability of calcium activated potassium ( K Ca) in rat hepatocytes. 目的观察甘氨脱氧胆酸(GDC)对大鼠肝细胞钙激活性钾通道(KCa)开放概率的影响。
These results demonstrate that NO activating KCa in resistance vascular smooth muscle was not only dependent on the pathway of cGMP/ PKG. 提示cGMP/PKG并非外源性NO激活KCa的唯一途径;
Results: Ca 2+-activated potassium channels ( K Ca channels) and ATP-sensitive potassium channels ( K ATP channels) could be activated by hypoxia which increased their open probability. 结果:缺氧引起钙激活钾通道(KCa通道)和ATP敏感性钾通道(KATP通道)的激活,增加通道的开放概率。
Conclusion: DS 201 directly activated both K ATP and K Ca. 结论:DS201对KATP和KCa均有直接激活作用。
CONCLUSION: The increasing of expression of KCa channel protein of capillary endothelial cell in glioma is probably one of the important factors in BK selectively opening blood-brain tumor barrier. 结论:KCa通道蛋白的表达增多可能是BK选择性开放BTB机制中的重要因素之一。
Conclusion High concentration glucose may reduce the biological functions of M ü ller cells by inhibiting calcium-activated potassium channel. 结论高浓度葡萄糖可能通过阻滞KCa通道而降低Müller细胞的生物学功能。
In the present work the mechanism of the effect of cGMP on KCa channel in primary cultured porcine coronary artery smooth muscle cells using patch clamp technique was investigated. 本工作应用膜片箝技术以原代培养猪冠状动脉平滑肌细胞为对象研究了cGMP影响KCa通道的机制。
Conclusion Both LPS and burn sera can lead to inhibition of the gastrointestinal motility by activation of KCa channels. 结论LPS和烧伤血清可通过激活肠道平滑肌细胞KCa抑制肠道蠕动。
The fractal aggregation models of materials, including diffusion limited aggregation ( DLA) model, kinetic cluster aggregation ( KCA) model, and diffusion and chemistry limited aggregation ( DCLA) model, are reported in this paper. 介绍若干材料中的分形凝聚模型:扩散限制凝聚(DLA)模型、动力学集团凝聚(KCA)模型和扩散与化学限制凝聚(DCLA)模型;
Expression of Kca mRNA in fetal and neonatal CD1 mice ductus arteriosus CD1小鼠动脉导管KcamRNA表达情况研究
Objective To study the effect of Danshensu ( DS-182) on calcium-activated potassium channel ( K_ ( Ca) channel) in cultured porcine coronary artery smooth muscle cells so as to elucidate possible ionic mechanism of coronary relaxation of DS-182 at the single potassium channel level. 目的观察丹参素(DS-182)对原代培养猪冠脉平滑肌细胞钙激活钾通道(KCa)的作用,从单个钾通道水平揭示其扩冠机制。
Results In hyperkalemic solution, the KCa conductance of colonic smooth mus-cle cells of the guinea pig was ( 271 ± 7) pS, indicating it was an ionic channel with high conductivity. 结果在对称性高钾溶液中,豚鼠结肠带平滑肌细胞内面向外式膜片上的KCa电导值为(271±7)ps,是高电导的离子通道。
Objective: To study the effect of sodium tanshinone ⅱ A sulfonate ( DS 201) on ATP sensitive potassium channels ( K ATP) and calcium activated potassium channels ( K Ca) in cultured smooth muscle cells of the porcine coronary artery. 目的:探讨丹参酮ⅡA磺酸钠(DS201)对原代培养猪冠脉平滑肌上ATP敏感的的钾通道(KATP)、钙激活钾通道(KCa)的作用。
Aim: To study the effects of nitric oxide on calcium-activated potassium channels ( KCa) in hypothalamus neurons. 目的:研究NO对下丘脑神经元钙激活钾通道(KCa)的作用及其机制。
Objective: To observe the calcium ion channel and potassium ion channel in the membrane of human umbilical vein endothelial cells ( HUVEC) cultured in vitro. 目的:观察体外培养人脐静脉内皮细胞膜上钙离子(Ca2+)通道和Ca2+激活的钾离子(Kca)通道。
Objective To study the regulation of Ca 2+ activated K+ channels ( KCa) of mesenteric artery smooth muscle cells,( SMC) in 18 old patients with essential hypertension ( EH) by endothelin-1 ( ET 1). 目的探讨内皮素1(ET1)对高血压病患者血管平滑肌细胞KCa通道活性的影响。
AIM: To investigate the role of Ca2+-activated, delayed-rectifier and ATP sensitive K+ channel ( KCa, Kdr, KATP) in airway hyperresponsiveness of asthmatic guinea pigs. 目的:探讨钙激活钾通道(KCa)、延迟整流型钾通道(Kdr)和ATP敏感型钾通道(KATP)在哮喘豚鼠气道高反应中的作用。
The potent vasodilation of it was induced primarily by inhibiting extracellular Ca2+ influx and partially by inhibiting intracellular Ca2+ release, as well as the activation of KCa channels. 其舒张作用机制主要是通过抑制外钙内流,部分可通过激活KCa和抑制内钙释放。
The results indicated that voltage-gated potassium currents and calcium-activated K+ currents can be recorded under given conditions. 结果表明在一定的实验条件下可记录出钙激活性钾电流(Kca)和电压门控性钾电流(Kv)。