This review will mainly discuss the research progress, clinical applications, anticancer activity mechanism, and their structure-activity relationship of indolocarbazole derivatives. 本文综述了吲哚咔唑类化合物的研究进展、临床应用、抗肿瘤活性产生的机制以及化合物的构效关系等。
3D-QSAR and Molecular Docking Study on Selectivity of Indolocarbazole Series as Cyclin-Dependent Kinase Inhibitors 3D-QSAR和分子对接研究吲哚咔唑类细胞周期蛋白激酶抑制剂的选择性
The obtained results are as follows: ( 1) Three N-hexadecyl indolocarbazole derivatives were synthesized. 本文取得的阶段性成果如下:(1)合成了3个不同弧度的N-十六烷基取代的吲哚并咔唑衍生物分子。