AIM: To construct phage human anti idiotypic antibody library. 目的:构建噬菌体人源抗独特型抗体库。
Construction of Expression Plasmid for Fused Idiotypic DNA Vaccine of B-cell Lymphoma 融合型B细胞淋巴瘤独特型DNA疫苗表达质粒的构建
TCR idiotypic DNA vaccine may generate anti-idiotypic immunity against the tumor. 应用TCR独特型DNA疫苗有可能激发抗肿瘤独特型免疫反应。
The detection approach based on multi-mutation-pattern artificial idiotypic network is compared with the detection approach based on multilayer perceptrons through simulations. The results show that the average false positive rate is decreased by 17.43% and the average detection accuracy of unknown attacks is increased by 24.27%. 仿真结果表明,多变异模式独特型网络检测方法与多层感知器检测方法相比,平均误报率下降了17.43%,未知攻击的平均检测准确率提高了24.17%。
Competitive inhibition assay indicated that 4 out of the 22 positive clones could display β or γ type anti idiotypic antibody ( anti Id) ScFv. 竞争抑制实验表明,在22个阳性克隆中有4个克隆所呈现的抗IdScFv属β或γ型。
The application of the anti idiotypic antibodies against blocking antibodies to recurrent spontaneous abortion 封闭抗体的抗独特型抗体在反复自然流产中的应用价值
Influence of idiotypic network regulation on renal transplant 独特型网络调节对移植肾的影响
The Experimental Study on the Idiotypic Nucleic Acid Vaccine Constructed from the Genomic DNA to Lymphoma 用基因组DNA制备独特型抗淋巴瘤核酸疫苗的实验研究
BACKGROUND OBJECTIVE: The potential of anti idiotypic antibody as a surrogate of tumor antigen for cancer therapy has been demonstrated in clinical investigations. 背景与目的:抗独特型抗体作为肿瘤抗原替代物可用于肿瘤治疗,这已在临床试验中得到证实。
Based on the response process of human immune system and the hypothesis of idiotypic immune network, a new network model of artificial immune response was proposed. The model was inspired by the mechanism of bindings, stimulus and replication of the B cells in the immune response. 根据人类免疫系统的免疫响应过程和免疫学中独特型免疫网络的假设,从免疫响应中B细胞的结合、B细胞的激励以及复制等方面入手,提出了建立人工免疫响应网络模型的新思想。
Screening and identification of a human Fab antibody against idiotypic antibody from a phage-display library of schistosoma japonicum 人源日本血吸虫Fab抗体库的构建及抗独特型抗体的筛选、鉴定
Based on idiotypic network theory and Multiagent system theory, a novel artificial immune system model, idiotypic network based on Multiagent and corresponding algorithm, are proposed. 基于独特型免疫网络理论和Multiagent系统理论,本文提出了一种新的人工免疫系统模型-基于Multiagent独特型免疫网络,并且给出相应的算法。
Selection and preliminary identification of monoclonal idiotypic antibody of Schistosoma japonicum 日本血吸虫单克隆独特型抗体的筛选及初步鉴定
Idiotypic DNa Vaccines for B-cell Lymphoma Induce Specific Immune Responses in Vivo B细胞淋巴瘤独特型DNA疫苗诱导特异性免疫反应的实验研究
CONCLUSION: A monoclonal anti-idiotypic antibody with an "internal image" of cervical cancer antigen was obtained. 结论:获得一株具有宫颈癌抗原内影像的抗独特型单克隆抗体。
Vehicle's Multi-sensor Fusion Algorithm Based on Idiotypic Network Theory 基于独特型网络理论的车载多传感器信息融合算法
Introduces the principle of immune system and idiotypic networks. 简要介绍了免疫系统的基本概念,以及人工免疫系统中的独特型网络模型,将其算法思想引入推荐系统中,提出了一种基于人工免疫系统的推荐算法。
To overcome defects existing in methods based on neural networks, such as the periodical update on detectors and poor performance on unknown attacks, the memory, learning and dynamic regulating abilities of artificial idiotypic networks are used to implement intrusion detection approaches. 为解决神经网络检测方法中检测器需要定期更新、未知攻击检测性能低等问题,利用人工独特型网络的记忆、学习和动态调整能力实现入侵检测。
Study on Idiotypic Cross-Reactivity among Murine Monoclonal Antibodies to Thyroglobulin 针对不同抗原决定簇的抗甲状腺球蛋白单克隆抗体间存在交叉反应独特型
A modeling study of acquired immune tolerance due to idiotypic network 独特型网络AB模型免疫耐受的研究
But at present, many anti idiotypic antibodies are mouse original antibodies, which can cause human anti mouse antibody ( HAMA) response and decrease the curative effect. 但由于目前所使用的抗独特型抗体多为鼠源性,用于人体可产生人抗鼠抗体反应,从而影响疗效。
Objective To determine the anti-trophoblast anti-body, blocking antibody and anti-idiotypic antibody on the onset of pre-eclampsia. 目的:观察滋养细胞膜抗体、封闭抗体及其抗独特型抗体水平对子痫前期发病的影响。
Experimental study on TCR β idiotypic antigenic determinants DNA vaccine to induce anti-lymphoma antibodies T细胞受体β独特型抗原决定簇DNA疫苗诱导抗淋巴瘤抗体的研究
Modulation of Anti-Idiotypes to Idiotypic Antibodies 抗独特型对独特型抗体的调节
Preparation of the anti-AIV ( H9)-idiotypic monoclonal antibody and the investigation on its immunogenicity 抗AIV(H9)独特型单克隆抗体的制备及其免疫原性的研究
Studies on the Idiotypic Network Regulation of Immune Systems in Theoretical Biology 理论生物学中关于免疫网络调节的研究
Objective To investigate the anti-human CEM lymphoma cell activities induced by TCR idiotypic DNA vaccine containing different antigen determinants in BALB/ c mice. 目的观察T细胞受体(TCR)β不同独特型抗原决定簇DNA疫苗诱导BalbC小鼠抗人类CEM淋巴瘤细胞免疫反应的情况。
Establishment and Biological Properties of Hybridoma Cell Lines Secreting Anti-AIV ( H_9N_2) Idiotypic Antibodies 抗AIV(H9N2)抗体独特型杂交瘤细胞株的建立及其产物生物学特性的研究