Results The composite showed some features of natural bone in both composition and microstructure. After implanting, the patients were not hyperpyrexial, did not have extravasate and immunoreaction, the bone defects were healing well. 结果纳米晶胶原基骨材料在成分与微结构上与天然骨类似,种植人体后患者无高热、渗出和免疫排斥反应,骨修复情况良好。