Objective To investigate the correlations between esophageal visceral hyperesthesia and the expression of substance P ( SP) immunoreactive fibers in the lower esophageal sphincter ( LES). 目的研究非糜烂性胃食管反流病(NERD)患者食管内脏感觉过敏与食管下端括约肌(LES)黏膜中P物质(SP)免疫反应阳性产物表达之间的关系。
Lots of diseases come with dysfunctions to the sensory system, causing hypoesthesia or hyperesthesia. 临床上的许多疾病的过程往往伴随着人体感觉功能的变化,引起感觉迟钝或过敏。
Relationship between esophageal visceral hyperesthesia and expression of substance P in LES of patients with non-erosive gastro-oesophageal reflux disease 非糜烂性胃食管反流病患者食管内脏感觉过敏与P物质表达的关系
Diarrhea-predominant IBS is the major type of IBS in China, the pathogenetic mechanisms of IBS-D are complicated, including visceral hyperesthesia, enhanced colonic motility, brain-gut dysfunction, abnormal neuro-immuno-endocrine network and so on. 腹泻型肠易激综合征(IBS-D)是我国IBS最常见的类型,其发病机制复杂,包括内脏感觉过敏、肠道动力增强、脑肠作用异常、神经-内分泌-免疫网络异常等。