Aim To study asymmetric total synthesis of 14 nor huperzine A 2 and its inhibitory activity on acetylcholinesterase. 目的(-)14去甲基石杉碱甲的合成及其抑制乙酰胆碱酯酶活性研究。
The Clinical Study of Huperzine A in the Treatment of Vascular Dementia 石杉碱甲治疗血管性痴呆的临床研究
Huperzine A Producing Conditions from Endophytic Fungus in SHB Huperzia Serrata 千层塔内生真菌SHB发酵产石杉碱甲条件的研究
Reviews of separation and determination of Huperzine A and its main plant sources 石杉碱甲的分离检测方法及主体植物源的研究进展
The Effect of Huperzine on Cognitive Dysfunction After Abdomenal Surgery in elder Patients 石杉碱甲对老年患者腹部手术后认知功能障碍的双盲研究
AIM: To evaluate the clinical efficacy and safety of huperzine A in treating Alzheimer diseases ( AD). 目的:观察石杉碱甲治疗阿尔采末病(AD)的疗效和安全性。
Puerarin and Huperzine A improve learning memory dysfunction induced by ischemia-reperfusion in mice 葛根素与石杉碱甲改善缺血-再灌注小鼠学习记忆
The total synthesis, structural modification and structure-activity relationship of huperzine A have been systematically reviewed. 本文系统地综述了石杉碱甲的全合成方法、结构改造工作及构效关系的研究。
Bioequivalence study of huperzine A in healthy volunteers with HPLC/ MS/ MS 液相色谱质谱联用技术研究石杉碱甲人体生物等效性
Huperzine A has been shown to be a powerful selective inhibitor of acetylcholinesterase and has attracted widespread attention because of its unique pharmacological profile and low toxicity. 摘要石杉碱甲是一高效、高选择性乙酰胆碱酯酶抑制剂,由于其独特的药理特徵和低毒性,引起了人们的广泛注意。
Influence of radio sterilization on the pharmacy characteristics of huperzine A injectable microspheres 辐射灭菌对石杉碱甲注射微球药剂学性质的影响
The role of huperzine as a mind booster in young individuals is not clear at this time. 它对年青人提高记忆的作用目前尚不清楚。
Objective: To observe the clinical efficacy of huperzine on cognitive function of schizophrenia. 目的探讨石杉碱甲治疗精神分裂症认知功能障碍的疗效。
Research of the Patients with Vascular Cognitive Impairment no Dementia in Terms of Neuropsychology and the Clinical Study of Huperzine A in the Treatment 非痴呆型血管性认知功能障碍患者神经心理学特点及石杉碱甲的临床疗效观察
Determination of the Content of Huperzine A in Huperzia serrata from Three Different Populations of Huaihua Region, Hunan Province 怀化地区蛇足石杉三个居群的石杉碱甲含量的测定
Selection of Huperzine A High-producing Strain by Physical and Chemical Mutation 物理与化学诱变筛选产石杉碱甲高产菌株的研究
Determination of huperzine A in rat plasma and brain tissue by HPLC method 高效液相法测定石杉碱甲在大鼠血浆和脑组织中的浓度
Preparation of Huperzine A Double-layer Sustained Release Tablets and Their in Vitro Release Characteristics Studies on the Factors Influencing Oleanolic Acid Release from Matrix Tablets 石杉碱甲双层缓释片的研制及体外释药研究齐墩果酸骨架缓释片释药影响因素的考察
Objective To evaluate the clinical efficacy and safety of huperzine A in treatment of patients with mild to moderate Alzheimer disease ( AD). 目的与安慰剂双盲对照评估石杉碱甲治疗轻、中度阿尔茨海默病(AD)患者的临床疗效和安全性。
AIM: To predict possible drug interaction and assure safety medication of huperzine A ( HupA). 目的:预测石杉碱甲可能的药物相互作用和确保石杉碱甲的用药安全。
OBJECTIVE To determine the absorption of huperzine A in various intestine segments in rats. 目的研究石杉碱甲在大鼠小肠及各肠段的吸收动力学特征。
CONCLUSION: Huperzine A can effectively improve memory and cognitive function in patients with organic brain diseases and has good curative effects. 结论:石杉碱甲能有效改善脑器质性疾病患者记忆和认知能力,具有较好的疗效。
AIM: To establish HPLC method for the determination of huperzine A in its preparation. 目的:采用HPLC方法测定石杉碱甲及其制剂的含量。
OBJECTIVE To establish a HPLC-Fluorescence method for the determination of the huperzine A in rat cerebrospinal fluid. 目的建立大鼠脑脊液中石杉碱甲的高效液相色谱-荧光测定方法。
Objective To evaluate the therapeutic effects of galanthamine hydrobromide capule ( GAL) which was used to treat Alzheimer disease ( AD) and compared to huperzine tablets. 目的观察氢溴酸加兰他敏胶囊(GAL)治疗轻、中度阿尔茨海默病(AD)的疗效和不良反应,并与哈伯因片剂相比较。
Objective: To study the anti dementia mechanism of Huperzine A. 目的:研究石杉碱甲对氧自由基的影响,探讨石杉碱甲抗老年性痴呆的机制。
Pharmacodynamics of in situ Gel and Tablets of Huperzine A in Impaired Memory Mice and Rats 石杉碱甲原位凝胶及片对记忆损害小鼠和大鼠的药效学研究
Huperzine A capsules vs tablets in treating senile amnesia: a double-blind study 石杉碱甲胶囊与片剂治疗良性衰老性遗忘症的双盲对照研究
This is a certain basis for further clinical development and application of Huperzine A and it will have a certain economic value and social significance. This paper studies include: 1. 本课题为HA的进一步开发应用提供了一定的研究基础,具有一定的经济价值和社会意义。
Huperzine A was used as the model for the verification of the developed method. 并以石杉碱甲为模型对本方法进行验证。