Study on Synthesis of 2,6-Dimethyl Heptanol 2,6-二甲基庚醇类香料合成工艺研究
METHODS: The effect of heptanol at different doses ( 0.03, 0.06, 0.30, and 0.60 mg/ kg) on the intact rat heart during 30 min ischemia ( ligation of left anterior descending coronary artery) and 2 h of reperfusion was observed. 方法:在体大鼠实验模型,结扎冠状动脉左前降支30min和复灌2h,观察不同剂量的庚醇(0.03、0.06、0.30和0.60mg/kg)的作用;
AIM: To determine the effect of heptanol on the in vivo heart subjected to ischemia and reperfusion, on the whole-tissue resistance and electrical uncoupling in the isolated rat heart during prolonged ischemia. 目的:在整体大鼠心脏缺血-再灌注损伤模型上研究庚醇的心肌保护作用,并在离体缺氧心脏模型上观察庚醇对电耦联参数的影响。
Carvedilol and heptanol can change the conductibility of gap junction to reduce the indexes of the apoptosis and necrosis of myocardial cells. 庚醇、卡维地洛通过改变缝隙连接通讯以及其他方面的作用来减少心肌细胞的死亡和凋亡。
AIM: To investigate the gap junctional intercellular communication in different ischemia/ reperfusion time, analyze the relation of gap junctional communication with myocytes necrosis and apoptosis, and study the interventional effect of carvedilol and heptanol. 目的:了解不同缺血再灌注时间心肌细胞缝隙连接通讯改变情况,分析心肌细胞缝隙连接通讯与心肌细胞坏死、凋亡的关系以及卡维地洛、庚醇的干预作用。
In heptanol treated cells, transmission remarkably reduced, and fluorescence only recovered to the second row. 运用庚醇后传导明显减慢荧光仅传至第二列细胞,缺氧和再供氧时传导也无明显变化。
Heptanol, a gap junction uncoupler, protects heart against ischemia-reperfusion injury in rats 缝隙连接脱耦联剂庚醇对大鼠缺血-再灌注损伤心肌的保护作用
Effect of heptanol on action potential of papillary muscle in the right ventricle of rat 庚醇对大鼠右心室乳头肌动作电位的影响
Based on the reaction product pentanal, pentanol, pentanoic acid, amylamine, 2-propyl heptanol and so on could also be generated, which mentioned above are all currently demanded chemicals for domestic and foreign. 由其反应产物正戊醛出发,可以进一步生成正戊醇、正戊酸、正戊胺、2-丙基庚醇等,均为目前国内外需求旺盛的化学品。
The results are as follows: 1. The percolation phenomenon was apparently resisted by toluene in the water/ AOT/ decanol system, while no effect in the water/ AOT/ heptanol system. 结果如下:1.甲苯对水/AOT/癸醇反相微乳液体系电导渗滤有明显的抑制作用,而对水/AOT/庚醇体系没有影响。