Methods In the present experiment, UA in the serum was studied in78 HAPC patients and80 healthy controls at highland. 方法选择HAPC患者78例,采集患者静脉血检测血清中尿酸的含量,并与80例高原健康人作对照研究。
Conclusion The study indicates that UA should be concentrated on in the patients with HAPC. 结论在治疗高原红细胞增多症时应关注患者血尿酸水平。
AIM: To study the changes of excretive amount of albumin ( ALB), N-acetyl-beta-D-glucosaminidase ( NAG) in patients with high altitude polycythemia ( HAPC) at different altitude and its mechanism. 目的:研究不同海拔高度高原红细胞增多症(HAPC)患者尿白蛋白(ALB)和N-乙酰-β-D-氨基葡糖苷酶(NAG)的排泄变化及其与红细胞生物物理特性的关系。
Effects of plasmin capsules on Antioxidation and endothelial function in patients with high altitude polycythemia 溶栓胶囊对HAPC患者抗氧化能力及内皮功能的影响
The result showed that HAPC, with obvious leukogenic effect, could inhibit immune damage of antitumor chemical cyclophosphamide ( CTX). 结果表明HAPC具有明显的升白作用,可对抗环磷酰胺对免疫系统的破坏作用。
The recombinant allophycocyanin ( HAPC) was expressed in E. coli P4/ pET-28a – APC. HAPC was purified by immobilized metal ion affinity chromatography and the purity reached above 90%. 含pET-28a/APC载体的大肠杆菌P4表达的重组别藻蓝蛋白HAPC,经金属螯合亲和层析法分离纯化,纯度达90%以上;
The forming rate of BFU-E in HAPC group was higher than that of control group ( P < 0. 01). 结论:观察中发现HAPC骨髓BFU&E集落产率与正常对照比较有显著差异(P<0.01),集落类型以多中心型,分散型为主。
Conclusions: It is suggested that there is different apoptosis in erythroid progenitor cells by comparing the HAPC with the normal. 结论:高原红细胞增多症红系祖细胞存在凋亡异常,需进一步研究是否存在基因表达异常。
Conclusion: Hypoxia induces elevated secretion of VEGF and the changes of VEGF may be related to hypoxic pulmonary hypertension, hypoxic adaptative regulation and complications of HAPC. 结论:高原缺氧诱导了VEGF分泌增多,VEGF在HAPC的肺动脉高压、低氧适应调节及并发症中可能发挥了重要作用。
Conclusion: The study indicated that it was related to disturbance or fibrinolysis coagulation system in the patients with HAPC and plasmin capsules were valuable in prevention and treatment of HAPC. 结论:高原红细胞增多症患者存在纤溶抑制功能的亢进及凝血与纤溶系统的紊乱,溶栓胶囊对高原红细胞增多症具有明显的防治效果。
Results: The membrane fluorescence polarization degree of erythrocyte was significantly increased and the membrane fluidity of erythrocyte remarkably decreased ( P < 0.01, P < 0.01). 结果:HAPC患者红细胞膜荧光偏振度与对照组比较增加(P<0.01)。红细胞膜过氧化脂质与对照组比较增高(P<0.01)。
A new 6 × His · tag recombinant allophycocyanin HAPC was efficiently expressed in E. 在工程菌株JM109中实现了带有6×His标记的新型重组别藻蓝蛋白HAPC的高效表达。
Objective To investigate the alteration of serum thyroid hormone level in the patients with high altitude polycythemia ( HAPC) and its clinical significance. 目的探讨高原红细胞增多症(HAPC)患者血清甲状腺激素的变化及其临床意义。
Objective: To study plasmin capsules on antioxidative capacity and endothelial function in patients with HAPC. 目的:观察运用溶栓胶囊治疗前后高原红细胞增多症患者抗氧化能力及内皮功能的变化,探讨其对高原红细胞增多症发生、发展的影响;
Objective To investigate the relationship between hyperhomocy ( Hcy) and oxygen free radical metabolism in patients with high altitude polycythemia ( HAPC) at different altitudes. 目的探讨不同海拔地区高原红细胞增多症(HAPC)患者体内同型半胱氨酸(Hcy)与氧自由基代谢水平的关系。
Objective To observe the changes of platelet parameter in the patients with high altitude polycythemia ( HAPC). 目的:探讨拉萨地区高原红细胞增多症(HAPC)患者血小板参数变化。
Objective: High altitude polycythemia ( HAPC) is a kind of polycythemia caused by hypoxia in high altitude areas. 目的:高原红细胞增多症是由慢性高原低氧引起的红细胞继发性过度增多。