glucuronidation
英
美
n. 葡（萄）糖醛酸轭合（作用）
双语例句
- RESULTS Distinct species differences can be observed in N+-glucuronidation. Commonly, this way is thought to be unique to man and non-human primates, but there are examples, however, of N+-glucuronidation occurring in lower animal species.
结果N+葡萄糖醛酸缀合反应具有明显的物种差异性，常被认为是高等灵长类所独有，但也有个别此类反应在低等实验动物中进行的报道。 - Objective To explore the developmental principle of UDP-glucuronosyltransferase 1A1 ( UGT1A1) activity in rat liver, provide experimental data for glucuronidation in neonate.
目的探讨大鼠肝脏发育不成熟期葡萄糖醛酸转移酶1A1活性的发育规律，为研究新生儿期葡萄糖醛酸结合反应提供实验依据。 - Influence of Phenobarbital Induction on the Stereoselectivity of Propranolol Glucuronidation in Rat Hepatic Microsome
苯巴比妥诱导对普萘洛尔对映体的体外葡醛酸缀合反应立体选择性的影响 - The basic group, the reaction promoter and the order of addition are all important variables in the glucuronidation.
糖基受体中的碱性基团、反应促进剂和加料顺序都是葡萄糖苷酸化反应的重要影响因素。化合物36和42分别经碱水解，制得苯丙哌林羟基化衍生物的葡萄糖苷酸21和22。 - Conclusion The major metabolic pathway of TBHQ in rat serum should be phase ⅱ reaction ( biotransformed by glucuronidation or arylsulfatation), although a small quantity of TBHQ would be metabolized by phase ⅰ reaction that might be oxidation.
结论TBHQ在大鼠血清中主要经Ⅱ相反应（与硫酸或葡萄糖醛酸结合）代谢，此外少量TBHQ会发生Ⅰ相反应，推测为氧化反应，生成的二羟基化物与谷氨酸结合。 - Effect of changes in lipid composition and fluidity of hepatic microsome membrane on bilirubin glucuronidation
肝脏微粒体膜脂质成分及膜流动性变化对胆红素葡萄糖醛酸化的影响 - Glucuronidation in Humans and Related Factors
人体内的葡醛酸结合反应及其影响因素 - Conclusion In vitro, trans T metabolism, M1 formation and M1 glucuronidation were found to be stereoselective in rat liver microsomes.
结论transT代谢，M1生成及其与葡糖醛酸结合均具立体选择性和性别差异； - Study on the stereoselectivity of racemic propranolol glucuronidation metabolism
普萘洛尔对映体人体葡醛酸化立体选择性代谢研究 - Glucuronidation of kaempferol in Ginkgo biloba flavonoid in vitro
银杏黄酮山奈酚的体外葡醛酸结合反应 - Objective: To obtain the information on the glucuronidation of Ginkgo flavonoid and the interaction profile of Ginkgo flavones with other drugs in vitro.
目的：获得银杏黄酮体外代谢情况，预测银杏叶制剂与常用心血管类药物之间的代谢性相互作用的可能性。 - METHOD: The structure and function of UGTs, gene polymorphism, expression specification in tissues, scope of drug glucuronidation and factors affecting drug glucuronidation in humans were summarized.
方法：从UGTs的结构和作用，UGTs的基因结构和基因多态性，UGTs的组织分布，药物在人体内葡醛酸结合反应的范围，影响UGT活性变化的因素等方面分别进行总结。 - OBJECTIVE A HPLC method was developed to determine directly propranolol glucuronide in urine of healthy volunteers and evaluate the stereoselectivity of racemic propranolol glucuronidation metabolism.
目的测定健康志愿者口服一定量消旋普萘洛尔后尿中两种不同构型普萘洛尔葡醛酸苷的排泄量，研究普萘洛尔对映体人体葡醛酸化代谢的立体选择性。 - Species differences in N~+-glucuronidation
N~+-葡萄糖醛酸缀合反应的物种差异 - In addition, they also catalyze the glucuronidation of exogenous compounds such as carcinogen 、 toxic substance 、 and therapeutic drugs, playing a centra part in the detoxication and drugs clearance.
此外还催化外源化合物如致癌物、有毒物质和治疗用药物的糖基化反应，参与解毒反应和药物清除。 - Mammalian uridine diphosphate glycosyltransferase ( UGTs) use UDP-glucuronic acid as sugar donor, catalyze the glucuronidation of many endogenous substrates such as bile acids 、 steroids and so on, participating in their metabolism and balance regulation.
哺乳动物尿苷二磷酸糖基转移酶（UGTs）利用UDP-葡萄糖醛酸作为糖供体，催化许多内源底物如胆汁酸、类固醇等化合物的糖基化，参与其在体内的代谢和平衡调节。