OBJECTIVE To exam the glibenclamide added in Shiwei Yuquan capsule. 目的检测十味玉泉胶囊中添加的格列苯脲。
OBJECTIVE To establish a method for the identification of glibenclamide, gliclazide, glimepiride which mixed in a Chinese patent medicine Tangleshu capsules. 目的建立唐乐舒胶囊中非法添加格列本脲、格列齐特、格列美脲成分的鉴别方法。
The Effect of Low Dose Glibenclamide on Secondary Lesion of Rat with Acute Spinal Cord Injury 小剂量格列本脲对大鼠急性脊髓损伤后继发性损害的影响
Preparation of compound metformin hydrochloride glibenclamide tablets Biological transport of glybenclamide by two kinds of osteoblasts 复方盐酸二甲双胍格列本脲片的研制比较两种成骨细胞对格列本脲的转运
Preparation and Characterization of Hydroxypropyl-β-cyclodextrin/ Glibenclamide Inclusion Complex 羟丙基-β-环糊精/格列本脲包结物的制备及其表征
The Effect of Glibenclamide on the K~+-ATP Channels of Pancreatic β TC3 with the Pretreatment of Amylin 胰淀素对优降糖作用于胰岛βTC3细胞ATP敏感性钾通道的影响
Research on Dissolution Rate and Bioequivalence of Glibenclamide and Metformin Compound Tablets; Determination of two components in metformin hydrochloride and glibenclamide tablets by ion-pair HPLC method 复方二甲双胍格列本脲片溶出度及生物等效性研究二甲双胍格列本脲片中两种成分的离子对HPLC法测定
Pharmacokinetics and Relative Bioavailability of Metformin-glibenclamide Release Tablets; Determination of two components in metformin hydrochloride and glibenclamide tablets by ion-pair HPLC method 格列本脲二甲双胍片健康人体药动学和相对生物利用度研究二甲双胍格列本脲片中两种成分的离子对HPLC法测定
Determination of two components in metformin hydrochloride and glibenclamide tablets by ion-pair HPLC method 二甲双胍格列本脲片中两种成分的离子对HPLC法测定格列美脲与格列苯脲治疗2型糖尿病的临床观察
Furthermore, hypothalamic dominant-negative Kir6.2 expression or the delivery of the KATP channel blocker glibenclamide abolished the glucose production-lowering effects of OAG. 此外,下丘脑显性负相Kir2的表达或使用KATP通道阻滞剂格列本脲能抵消OAG的作用减少葡萄糖生成的作用。
An increased risk of cardiovascular death was associated to treatment with glimeperide, glibenclamide, glipizide, and tolbutamide when compared with metformin ( Figure). 与二甲双胍相比当使用格列美脲、格列苯脲、格列吡嗪及甲苯磺丁脲降糖治疗时心源性死亡的风险增加。
Preparation of Glibenclamide Solid Dispersion and Compound Glibenclamide Capsules 格列本脲固体分散体及其复方胶囊剂的研制
OBJECTIVE To establish an HPLC method for determining glibenclamide in Xiaokeping granules. 目的建立测定消渴平颗粒中格列本脲含量的方法。
Determination of Three Related Substances in Metformin Hydrochloride and Glibenclamide Tablets by HPLC HPLC测定复方盐酸二甲双胍格列苯脲中3种有关物质
RESULTS Glibenclamide was detected in Shiwei Yuquan capsule. 结果供试品中检出了格列苯脲。
Glibenclamide was used in B and D groups to inhibit ATP-sensitive potassium channels before ischemia. 其B和D组在缺血前以优降糖阻止心肌ATP敏感性钾通道的开放。
AIM To study the bioequivalence of domestic compound metformin hydrochloride tablet ( tested preparation) and glibenclamide tablet, metformin hydrochloride tablet ( reference preparation) in healthy volunteers. 目的研究试验制剂国产复方盐酸二甲双胍片与参比制剂格列本脲片、盐酸二甲双胍片的人体生物等效性。
Daily cost of glibenclamide and metformin was low, and gliquidone was medium and rosiglitazone was expensive. 格列本脲、二甲双胍每日药费较低,格列喹酮价格适中,罗格列酮属价格较高品种。
The comparative analysis revealed that gliclazide, glurenorm and glibenclamide were the main oral hypoglycemic agents in our hospital. 临床用药量动态分析表明格列齐特、格列喹酮、格列本脲(优降糖)为武汉协和医院主要的口服降血糖药。
CONCLUSION: The main components of CMGC, metformin and glibenclamide, are bioequivalent to the reference tablets, MT and GT. OBJECTIVE: To establish a HPLC method for the determination of foreign substance dicyanodiamide in com ˉ pound metformin and glibenclamide tablets. 结论:复方二甲双胍胶囊中二甲双胍和格列本脲与参比药相比皆生物等效目的:建立以高效液相色谱法测定复方二甲双胍格列本脲片中杂质双氰胺含量的方法。
The content uniformity and dissolution uniformity of glibenclamide in compoundmetformin hydro-chloride capsules prepared respectively by solvent dispersing method and micronization were compared. 比较了分别采用溶剂分散法和微粉化法制备的复方盐酸二甲双胍胶囊中格列本脲的含量均匀度及溶出均一性。
HPLC-FA Study on the Protein Binding of Glibenclamide 格列本脲蛋白结合作用的HPLC-FA法研究
OBJECTIVE To study the pharmacokinetics and bioequivalence of fixed-tablet glibenclamide/ metformin in healthy volunteers. 目的研究复方格列本脲片在健康人体内的药物动力学及评价复方格列本脲片相对于格列本脲片与二甲双胍片联用是否具有生物等效性。
Objective: To develop an RP-HPLC method for the assay of metformin hydrochloride and glibenclamide in compound metformin hydrochloride tablets. 目的:建立HPLC方法测定新药复方盐酸二甲双胍片中盐酸二甲双胍和格列本脲的含量。
OBJECTIVE: To study the effects of nifedipine and the interaction of nifedipine and glibenclamide on the plasma glucose levels in the fasted and adrenaline hydrochloride induced hyperglycemic rat. METHODS: Plasma glucose was measured with glucose oxidase method. 目的:研究硝苯吡啶以及硝苯吡啶与格列本脲合用对空腹大鼠和肾上腺素诱发高血糖大鼠血糖水平的影响。方法:本实验采用葡萄糖氧化酶法测定血糖含量。
Objective: To prepare the compound glibenclamide tablets. 目的:制备复方格列本脲片。
To establish a method of determine the dissolution of glibenclamide. 建立格列本脲溶出方法。