geldanamycin
英
美
n. 格尔德霉素
双语例句
- Although there was much preclinical interest in the antibiotic geldanamycin as an anti-cancer drug, it turned out to be a poor candidate for clinical trials because of its toxicity.
尽管在临床前试验中抗生素格尔德霉素表现出很强的作为抗癌药物的潜力，但是因为其毒性，这种药物没有能成为具有良好临床试验前景的候选药物。 - Analysis of geldanamycin analogues in trace amounts by LC-MS/ MS
高效液相色谱-串联质谱分析微量格尔德霉素类似物 - Experimental Study on Glioma Treated by Geldanamycin and Correlated with Hepatocyte Growth Factor
格尔德霉素治疗脑胶质瘤及其与肝细胞生长因子相关性研究 - AIM To study the effect of geldanamycin ( GDM) on cell cycle of human hepatoma BEL 7402 cells and the antitumor activity of cisplatin and mitomycin C in combination with GDM in vitro and in vivo.
目的研究格尔德霉素（Geldanamycin，GDM）对人肝癌BEL7402细胞周期的影响及顺铂和丝裂霉素C等药物联用GDM后的体外体内抗肿瘤作用。 - Geldanamycin ( GA) is an antibiotic with its primary target on the ADP/ ATP binding site of heat shock protein 90 ( Hsp90).
格尔德霉素（GA）是一种抗生素，它的作用靶点是热休克蛋白Hsp90N末端的ATP/ADP结合位点。 - The Studies on Geldanamycin Biosynthetic Gene Cluster in Streptomyces Hygroscopicus 17997
吸水链霉菌17997中格尔德霉素生物合成基因簇的研究 - Conclusion: The SPE-HPLC method for geldanamycin is accurate, rapid and simple with good reproducibility.
结论：固相萃取-HPLC法测定格尔德霉素准确，快速，回收率高。 - Geldanamycin inhibits the expression of oncogene in vivo and in vitro. It also affects the hot shock protein 90 ( Hsp90) by binding specifically with it.
格尔德霉素属苯醌型安莎类抗生素，它可在体内、外抑制癌基因表达产物，并可特异性地与热休克蛋白Hsp90结合影响其功能。 - The absorption of geldanamycin in eye drops by cornea of rabbits
格尔德霉素滴眼液兔眼角膜吸收的研究 - CONCLUSION: The compound SIPI-100-1 produced by Streptomyces hygroscopicus R-10 is identical with geldanamycin and its new immunosuppressant activity is first found.
结论：吸水链霉菌R-100合成的SIPI-100-1化合物属于安沙类抗生素，与文献报道的Geldanamycin结构一致，免疫抑制活性属于首次发现。 - Determination of the content and the related substances of geldanamycin in vaginal effervescent tablet by RP-HPLC
RP-HPLC法测定格尔德霉素阴道泡腾片的含量和有关物质