OBJECTIVE To develop a rapid analysis method by fiber-optic sensor for determining galanthamine hydrobromide injection spectrum and content rapidly. 目的建立一种光纤传感快速测定氢溴酸加兰他敏注射液光谱和含量的方法。
Study of Pharmacokinetic and Bioequivalence of Galanthamine Hydrobromide Orally Disintegrating Tablets in Human 氢溴酸加兰他敏口腔崩解片的人体药代动力学和生物等效性研究
The Study on the Effect and Mechanism of Acetylcholinesterase Inhibitor Galanthamine on Sepsis Inflammation 胆碱酯酶抑制剂加兰他敏对脓毒症炎症反应的作用及其机制研究
Preliminary evaluation of brain targeting via intranasal administration of galanthamine hydrobromide 氢溴酸加兰他敏经鼻脑靶向性初步评价
Studies on Intranasal Brain Drug Targeting Delivery System for Galanthamine Hydrobromide 氢溴酸加兰他敏鼻腔给药脑靶向传递系统的研究
Study of the release and transdermal permeation of the transdermal patch of galanthamine hydrobromide in vitro Effects of sodium hyaluronate on the physicochemical properties of ophthalmic thermosensitive in situ ge1s of diclofenac sodium 氢溴酸加兰他敏贴剂体外释药性和经皮渗透性能研究透明质酸钠对眼用温度敏感原位凝胶体外释放和粘附力的影响
Bioavailability of Single Oral Dose of Galanthamine Hydrobromide Extended-release Pellet Capsule in Dogs 家犬单剂量口服氢溴酸加兰他敏缓释微丸胶囊的生物利用度研究
This paper will review the novel advances in the mechanism of galanthamine treatment for Alzheimers disease. 本文就加兰他敏治疗阿尔茨海默病作用机制的最新研究情况作一简要概述。
Scientists in Finland found that the drug galanthamine provides an effective symptomatic treatment for patients with dementia. 芬兰科学家们发现加兰他敏药物可以对老年性痴呆患者提供有效的对症治疗。
Chemiluminescence Analysis of Galantamine Hydrobromide with a Nanometer Microreactor Extraction and HPLC determination of galanthamine and lycoramine in Lycoris radiata 纳米微反应器化学发光法测定氢溴酸加兰他敏石蒜中加兰他敏和力可拉敏的提取及高效液相色谱法分析
HPLC determination of buprenorphine in buprenorphine patches and its skin permeation behavior in vitro Study of the release and transdermal permeation of the transdermal patch of galanthamine hydrobromide in vitro HPLC法测定丁丙诺啡贴剂中药物的含量及其体外透皮释放量氢溴酸加兰他敏贴剂体外释药性和经皮渗透性能研究
Extraction and HPLC determination of galanthamine and lycoramine in Lycoris radiata A Test Study of Liparis kumokiri F.Maek Exists in the Northeast of China 石蒜中加兰他敏和力可拉敏的提取及高效液相色谱法分析曲唇羊耳蒜在中国东北分布的真实性研究
Rapid Analysis of Galanthamine Hydrobromide Injection by Fiber-optic Sensor 光纤传感快速分析氢溴酸加兰他敏注射液
Determination of galanthamine from different parts of Lycoris aurea herb with HPLC HPLC法测定黄花石蒜不同部位的加兰他敏含量
OBJECTIVE To Apply microwave assisted extraction to extract galanthamin in lycoris radiate. 目的运用微波辅助提取法(MAE)提取石蒜属植物忽地笑中的加兰他敏(Galanthamine)。
In mice, rabbits and cats, galanthamine hydrobromide was 2-8 times more toxic than lycoramine hydrobromide. The therapeutic index of the two alkaloids was similar. 力可立敏对小自鼠、家兔和猫的急性毒性作用此加兰他敏小2&8倍,其治疗指数接近加兰他敏。
Results Amnesia in mice can be prevented markedly after huperzine-A 0.4mg/ kg, Tacrine 40mg/ kg or Galanthamine 4.0mg/kg is administered. 结果ig石杉碱甲0.4mg/kg或他克林40mg/kg或加兰他敏4.0mg/kg均能使小鼠的记忆障碍得到显著的改善。
Separation of Galanthamine from Amaryllidaceae Family and the Application in Medicine 石蒜属植物中加兰他敏的分离提取及其应用
Determination of galanthamine in bulb of Lycoris radiata by RP-HPLC RP-HPLC测定石蒜中加兰他敏含量
Observation of effect on Alzheimer disease treated by Galanthamine hydrobromide capules 氢溴酸加兰他敏治疗阿尔海默病的疗效观察
Objective To evaluate the therapeutic effects of galanthamine hydrobromide capule ( GAL) which was used to treat Alzheimer disease ( AD) and compared to huperzine tablets. 目的观察氢溴酸加兰他敏胶囊(GAL)治疗轻、中度阿尔茨海默病(AD)的疗效和不良反应,并与哈伯因片剂相比较。
OBJECTIVE: To develop a HPLC-UV method to determine the concentration of galanthamine in human plasma and study its pharmacokinetic profiles and bioequivalence. 目的:建立加兰他敏血浆药物浓度的HPLC-UV检测法,研究其在人体的药代动力学和相对生物利用度。
An Improved Synthetic Method of Tyramine Using isovanillin and tyramine as the initial materials, racemic galanthamine was prepared in five steps including bromination, condensation and reduction, formylation, oxidation coupling and reduction. 酪胺制备的改进方法以异香草醛和酪胺为主要原料,经溴化、缩合还原、甲酰化、氧化偶合及还原五步反应,合成了外消旋加兰他敏。
Objective: To instigate both prescription and stability of galanthamine hydrobromide dispersion tablets. 目的:研究氢溴酸加兰他敏及其分散片的处方和制备工艺。
Therefore further study was needed to elucidate the relationship between COMT and the biosynthesis of galanthamine. 因此儿茶酚氧位甲基转移酶与加兰他敏生物合成的关系还需要进一步的研究加以明确。
Semi-quantitative RT-PCR indicated that there was some correlation between COMT gene expression and the accumulation of galanthamine in flowers, flower stalks, bulbs and roots. 该基因的定量RT-PCR分析表明,在花、花葶、鳞茎和根中,加兰他敏的含量与该部位COMT基因的表达量之间有一定的相关性,但并不完全一致。
Light can increase the content of Lycorine, Galanthamine and Lycoramine. 与暗条件下相比,光照能增加愈伤组织中石蒜碱、加兰他敏和力克拉敏的含量。
The galanthamine, lycorine and lycoramine content of Lycoris chinensis were researched during development from young to old plants. 研究了中国石蒜生长时间中加兰他敏、力克拉敏、石蒜碱含量的变化。
A putative segment of Catechol O-methyltransferase ( COMT) gene was obtained which has been proved to be related with biosynthesis of galanthamine. 克隆可能与加兰他敏生物合成相关的儿茶酚氧位甲基转移酶(COMT)基因的片段。