OBJECTIVE To investigate the composition and process of galantamine hydrobromide orally disintegrating tablets ( ODT). 目的探讨氢溴酸加兰他敏口腔崩解片的处方及制剂工艺。
Chemiluminescence Analysis of Galantamine Hydrobromide with a Nanometer Microreactor Extraction and HPLC determination of galanthamine and lycoramine in Lycoris radiata 纳米微反应器化学发光法测定氢溴酸加兰他敏石蒜中加兰他敏和力可拉敏的提取及高效液相色谱法分析
Galantamine is an alkaloid originally extracted from the bulbs of the plant Leucojum aestivum and shows reversible acetylcholinesterase ( AChE) inhibitory activity. 加兰他敏是从雪片莲中提取的一种生物碱,具有可逆性胆碱酯酶抑制活性。
Results In the AD model rats administered with galantamine, the performances in the test were significantly improved and ChAT immunoreactive positive neurons were increased significantly in hippocampus and cortex fields. 结果加兰他敏可明显提高痴呆模型大鼠在行为学测试中的成绩,使皮层、海马ChAT免疫阳性神经元数目增多。
Enantiomeric Separation of Galantamine in Drug for Alzheimer's Disease and Its Quality Control by Capillary Electrophoresis 抗痴呆症药中加兰他敏对映异构体的毛细管电泳分离及药物质量控制
AIM: To evaluate the therapeutic effects of galantamine on senile dementia and benign senescent forgetfulness. 目的:评估加兰他敏胶囊治疗老年性痴呆和单纯性记忆障碍的疗效。
Conclusions Galantamine is effective and safe to improve memory and cognitive function in AAMI and AD. 结论加兰他敏对改善AAMI及AD记忆及认知功能有一定疗效且可耐受。
Metabolic patterns associated with the clinical response to galantamine therapy: A fludeoxyglucose F 18 positron emission tomographic study 与加兰他敏治疗临床反应相关的代谢模式:氟(~(18)F)脱氧葡萄糖PET研究
It was reported that both of them blocked delayed rectifier potassium channels of rat hippocampal neurons in our previous study. 本室的前期研究表明,donepezil和galantamine可明显抑制大鼠海马神经元上的延迟整流钾通道,但它们对钾通道亚型的作用尚未见报道。
Galantamine vs piracetam in treatment of senile dementia and benign senescent forgetfulness 加兰他敏与吡拉西坦治疗老年性痴呆和良性衰老性遗忘症的比较
Methods The AD rat models established by injecting amyloid-beta protein ( A β 1-40) into the bilateral Meynert nucleus were intervened with galantamine, and their abilities of learning and memory were measured with a behavioral test. 方法将β淀粉样蛋白(Aβ)注入Meynert核制作大鼠痴呆模型,并用加兰他敏进行干预。
Objective To Observe The Efficacy and Adverse Drug Reactions of Galantamine in treating Age-associated memory impairment ( AAMI) and Alzheimer's Disease ( AD) By Double Blind Method. 目的观察加兰他敏对增龄相关记忆障碍(AAMI)及阿尔茨海默病(AD)疗效及副反应。
Galantamine were injected i.g at dose of lmg/ 100g/ day two weeks before experiment. 从实验前两周起至实验时止,以1mg/100g体重/天的剂量分别对铅暴露和对照组给与腹腔注射加兰他敏。