Urine proteins were separated by two-dimensional electrophoresis in32 patients with FSGS, lupus nephritis, membranous nephropathy, or diabetic nephropathy. 我们利用二维电泳技术对32例病人(包括FSGS、狼疮性肾炎或膜性肾病、糖尿病肾病)的尿液中的蛋白质进行了分离。
Logically, the possibility of a circulating factor associated with recurrence of FSGS led investigators to treat patients with plasmapheresis. 这种因子与FSGS复发之间的联系使得一些研究者顺理成章地使用血浆置换来治疗患者。
FSGS accounts for about a sixth of cases of nephrotic syndrome in adults and children. 成年人和儿童肾病综合征有1/6是局灶性节段性肾小球硬化。
Primary FSGS is an increasing cause of end-stage renal disease. 原发性FSGS是一种正在增长的终末期肾脏疾病的病因。
During follow-up24 patients developed RD, almost equally distributed between patients with and without FSGS. 在这24个发展到肾衰竭的随访病人,有和没有局灶节段性肾小球硬化的病人是相当的。
Renal surial was numerically, but not significantly, lower in patients with FSGS. 残余肾功能是存在的,但很少,在有局灶节段性肾小球硬化的病人是更低。
Some investigators have identified a circulating factor called the FSGS factor that appears to be associated with recurrence after transplantation. 一些研究者曾经鉴定出一种被称之为FSGS因子的循环因子,其与移植后FSGS复发相关联。
Familial forms of FSGS also exist due to alterations of several different podocyte proteins. 家族性FSGS也可因为某些不同的足突细胞蛋白改变而发生。
It has been suggested that focal segmental glomerulosclerosis ( FSGS) is a discriminative parameter with independent prognostic value. 认为局灶节段性肾小球硬化是一个有独立诊断价值的特别参数。
Recurrence of severe FSGS in renal allograft recipients presents a major challenge to transplant physicians. 异体肾脏移植受者严重的FSGS复发对移植医生来说是一个主要的挑战。
These patients were less likely to have responded to steroids and more likely to have FSGS on repeat renal biopsy. 这些患者较少的对激素治疗有反应,在反复进行的肾活检更多的有局灶性节段性肾小球硬化。
Objective To investigate the relationship between the clinical character and pathological variants as well as response to treatment of focal segmental glomerulosclerosis ( FSGS) in children. 目的探讨原发性局灶节段性肾小球硬化(FSGS)的临床表现、肾脏病理和治疗反应的特点及关系。
To observe the clinical effect of cyclosporine A ( CyA) treatment for focal segmental glomerulus sclerosis ( FSGS) clinically presenting as nephrotic syndrome in children, 11 nephrotic children with FSGS, aged from 2 to 11 years, were planned to received CyA treatment. 为了观察环孢霉素A(CyA)对以肾病综合征为表现的局灶节段性肾小球硬化(FSGS)的疗效。对11例病儿进行治疗,年龄2岁~11岁。
【 Conclusion 】 MsPGN MPGN and FSGS are most of the histological changes of RNS in children. 【结论】小儿难治性肾病病理改变以MsPGN、MPGN及FSGS最为常见。
Various clinical studies has confirmed that the FSGS has something to do with blood clotting and dissolving systemobstacle. 大量临床资料已证实,FSGS与凝血纤溶系统障碍有关。
This review discussed the recent progress in molecular genetics of congenital NS, autosomal recessive or dominant family focal segmental glomerulosclerosis ( FSGS), sporadic NS and symptomatic diffused mesangial sclerosis or FSGS. 该文主要讨论先天性NS、常染色体隐性或显性家族性局灶节段性肾小球硬化(FSGS)、散发性NS以及综合征性弥漫性系膜硬化(DMS)或FSGS的分子遗传学进展。
[ Conclusions] Among PGN, MsPGN is the most frequent pathology type, followed by FSGS and IgAN. 结论辽宁地区肾脏病病理类型中系膜增生性肾小球肾炎、局灶节段性肾小球硬化和IgAN是最常见的PGN;
Conclusion: The urinary TFG-β 1 level increased in FSGS group and was correlated to inflammatory cell infiltration and/ or fibrosis in interstitial tissues and the severity of proteinuria. 结论:FSGS患儿的尿液中TGF-β1水平升高,其与间质炎症细胞浸润及蛋白尿严重程度相关。
Results Focal segmental hyalinosis and intraglomerular foamy cells were characteristic of primary into FSGS for children. 结果:肾小球局灶节段性透明变性及间质泡沫细胞浸润在小儿原发性FSGS中是一个较为特征性的表现。
Objective To analyze the incidence, clinical presentations and pathological changes of patients with primary focal segmental glomerulosclerosis ( FSGS). 目的重新评价肾活检标本中特发性局灶节段性肾小球硬化病(FSGS)的发生率、主要临床及病理特点。
Objective: To investigate the morphological characteristics and expression of cell cycle regulatory proteins in cellular variants of idiopathic focal segmental glomerulosclerosis ( FSGS). 目的:探讨细胞型局灶节段性肾小球硬化症(Focalsegmentalglomerulosclerosis,FSGS)的病理学特征及其细胞周期调控蛋白的表达。
Objective: To investigate the relative frequency of idiopathic focal segmental glomerulosclerosis ( FSGS) in renal biopsy proven diseases, and its criteria and significance of clinicopathological diagnosis. 目的:了解特发性局灶节段性肾小球硬化症(Focalsegmentalglomerulosclerosis,FSGS)在肾脏疾病中的构成变化及其临床病理诊断要点和意义。
Objective: To evaluate the clinical significance of detection of urinary transforming growth factor-β 1 ( TGF-β 1) in children with focal segmental glomerulosclerosis ( FSGS). 目的:评估局灶节段性肾小球硬化(FSGS)患儿尿液中TGF-β1检测临床意义。
Objective: Focal Segmental Glomerulosclerosis ( FSGS) is a common non-inflammation sclerosis pathological change involved in the capillary and glomeruli, which is a common pathologic process of most kidney disease leading to renal failure. 目的:局灶节段性肾小球硬化(FSGS)是指病理学上累及部分肾小球中部分毛细血管袢的非炎症性硬化性病变,是各种肾小球疾病进展到终末期肾衰的共同病理途径。
Focal segmental glomerulosclerosis ( FSGS) came second in incidence, 20%. 其次为局灶节段性肾小球硬化,占20%;
Expression and implication of tissue transglutaminase in FSGS model rats with puromycin aminonucleoside nephropathy 组织型转谷氨酰胺酶在局灶节段性肾小球硬化大鼠肾脏中的表达和意义
The appearance of the secondary FSGS had a poor prognosis for glomerulonephritis. 出现继发性FSGS则是预后不良的表示。