Treatments include hormonal contraceptives to prompt ovaries to stop producing testosterone and other hormones, plus anti-androgen medications like flutamide, usually used to treat prostate cancer, and insulin sensitizers for metabolic issues. 治疗办法包括服用激素避孕药,促使卵巢停止产生睾丸激素和其他激素,服用通常用于治疗前列腺癌的氟他胺等抗雄激素药物,以及针对代谢问题服用胰岛素增敏剂。
She found that metformin, an insulin sensitizer called pioglitazone and flutamide taken together performed better than oral contraceptives. 她发现,二甲双胍、胰岛素增敏剂?格列酮和氟他胺一起服用的效果好于口服避孕药。
OBJECTIVE To develop an HPLC-MS/ MS method for the determination of2-hydroxyflutamide in human plasma and evaluate the bioequivalence of flutamide tablets. 目的建立人血浆中2-羟基氟他胺的HPLC-MS/MS测定法,研究氟他胺片生物等效性。
Establishment of an Androgen-independent Prostate Cancer Cell Line Induced by the Combined of Flutamide and Androgen-free Environment 氟他胺联合去雄激素环境诱导的雄激素非依赖性前列腺癌细胞模型的建立
Clinical effect of flutamide and metformin on patients with complicated polycystic ovary syndrome 氟他胺和二甲双胍在难治性多囊卵巢综合征中的临床应用
Objective To investigate the effects of flutamide on hyperplasia of prostate and its mechanism. 目的探讨氟硝丁酰胺抑制前列腺增生的作用及其机制。
Purpose: To investigate the effect of combined castration and flutamide therapy in patients with advanced prostate cancer. 目的:探讨缓退瘤治疗晚期前列腺癌的效果。
Objective To investigate the effect of flutamide on laryngeal carcinoma cell lines HEP-2 apoptosis. 目的观察氟硝丁酰胺对喉鳞癌细胞株HEP2的生长调控作用。
Objective To establish a rat model of hypospadias by flutamide to further studying molecular mechanisms of hypospadias etiology. 目的采用抗雄激素类药物氟他胺诱导建立大鼠尿道下裂动物模型,为进一步研究尿道下裂发病的分子作用机制和治疗提供理论和实验依据。
Pilot study on application of antiandrogen ( flutamide) in the treatment of congenital adrenal hyperplasia 雄激素拮抗剂氟他胺在先天性肾上腺皮质增生症治疗中应用探索
The inhibiting potency of dimethachlon was about 1/ 100 of that of flutamide. 菌核净的抑制作用较氟他胺弱,约为氟他胺的1/100。
The mechanism of testosterone secretion of F1 male rat with flutamide 氟他胺对F1雄性大鼠睾酮分泌的影响机制
Influence of Flutamide on Liver Biotransformation Enzymes and Antioxidation in Rats 氟他胺对大鼠肝生物转化酶和抗氧化功能的影响
Conclusions Medical castration plus flutamide is effective for the management of metastatic prostate cancer. 结论药物去势加雄激素阻断剂之全雄激素阻断疗法,治疗初发的转移性前列腺癌疗效肯定,去势稳定。
[ Purpose] To investigate the effect of bicalutamide for flutamide resistant prostate cancer. [目的]探讨康士得对于缓退瘤耐受的前列腺癌的疗效。
Change of androgen receptor in induced hepatoma and influence of flutamide on expression of androgen receptor and hepatocarcinogenesis 诱发性肝癌雄性激素受体的动态变化及氟他胺对受体表达和成癌的影响
Conclusion Inhibition of flutamide on hyperplasia of prostate is associated with antagonizing the effect of androgen. 结论氟硝丁酰胺通过拮抗雄激素作用而抑制前列腺增生。
Orchiectomy with Oral Flutamide in Treating Advanced Prostate Carcinoma& Clinical Report of 22 Cases 氟他胺加睾丸切除治疗晚期前列腺癌22例报告
Objective To observe the clinical effect of advanced prostate cancer treated by Zoladex and Flutamide, and analyze the related factors influencing curative effect. 目的观察诺雷德(Zoladex)和氟他胺(Flutamide)治疗晚期前列腺癌的临床疗效,分析影响疗效的有关因素。
Research on Synthesis of Anticancer Drug Flutamide 抗癌药氟他胺的合成研究
Methods 24 cases of advanced prostate cancer ( 10 in stage C and 14 in stage D) were retrospectively studied. All the patients have been treated with combined androgen blockade ( bilateral orchiectomy and flutamide). 方法对24例前列腺癌(C期10例,D期14例)采用联合雄激素阻断(双侧睾丸切除+氟他胺)治疗。
Impact of Flutamide on Sex Differentiation in Rats 小剂量氟他胺对大鼠性分化影响的实验研究
Mechanism of Antiandrogen Flutamide Causing Hypospadias on Pregnant SD Rat 抗雄激素物质氟他胺作用于受孕SD大鼠引起尿道下裂的机制研究
Methods Flutamide was added to LNCaP cells. The mRNA from both experiment group cells and the control group cells was extracted to make cDNA probes. The difference in the expression of cell cycle related genes was observed in both groups by genechips. 方法在LNCaP细胞中加入氟他胺,然后抽提正常LNCaP细胞和加入氟他胺的LNCaP细胞中的mRNA制备cDNA探针,应用基因芯片技术观察两者细胞周期基因表达差异情况。
AIM: To study the atrophy and apoptosis effect of flutamide ( Flu) and2 hydroxyflutamide ( HF) on the benign prostatic hypertrophy ( BPH) of rats. 目的:研究氟他胺与2羟基氟他胺对诱导的前列腺增生大鼠前列腺萎缩和细胞凋亡的作用。
Objective To evaluate the efficacy of medical castration plus flutamide in the treatment of metastatic prostate cancer. 目的观察药物去势加雄激素阻断剂&缓退瘤(Flutamide)之全雄激素阻断疗法治疗转移性前列腺癌疗效。
Cases had not decreased to normal PSA, plus flutamide adjuvant hormone therapy, they gradually returned to normal. 2例术后PSA未降至正常,加用氟他胺行辅助内分泌治疗后逐渐降至正常。
The growth characteristics and androgen-dependence of the three LNCaP sublines were determined by flutamide and DHT in vivo and in vitro. 然后用双氢睾酮和氟他胺在体内和体外实验中对上述三种LNCaP前列腺癌亚细胞株的生长特性及其雄激素依赖性进行研究,以论证所建立的前列腺癌细胞模型。