It could inhibit human platelet aggregation induced by ADP, collagen without activities of phospholipase A2, esterase, fibrinogenolytic. 该物质无磷脂酶A2、精氨酸酯酶及纤溶酶活性,具有拮抗ADP、胶原诱导的血小板聚集作用。
Snake venom thrombin-like enzymes belong to the fibrinogenolytic enzyme family and are serine proteases. 蛇毒类凝血酶属于纤维蛋白原裂解酶,是一种丝氨酸蛋白酶。
EDTA hampered the activity, suggesting that metal ion ( s), in particular transition metal ions, played a role in the fibrinogenolytic process. EDTA阻碍了重组酶的纤维蛋白原裂解活力,提示金属离子尤其是过渡金属离子在纤维蛋白原裂解过程发挥了作用。
However, TPCK did not affect the fibrinogenolytic activity but affect amidolytic activity. 可是TPCK只影响了酰胺水解活力,却对纤维蛋白原裂解活力没有影响。