The understanding of this association may offer assistance of the clinical classification of FALS and diagnosis of subclinical FALS. 若能探明前两者与后者的关系,将有助于FALS的临床分型及亚临床诊断。
So far, 20 percent of fALS and 4% Sporadic amyotrophic lateral sclerosis ( sALS) have the SOD1 gene mutation and more than 100 kinds of mutation have been identified. 到目前为止,已确定在20%fALS和4%的散发性肌萎缩侧索硬化(sALS)中有SOD1基因突变,其突变数目已超过100种。
But the detection mechanisms of traditional IDSs has weaknesses including too fine grain, isolated alarming, lack of environmental consciousness and high rate of fals alarms. 但是,传统IDS的检测机制具有细粒度、孤立性、弱的环境意识、误报率高等缺点。