Hyperlipidemia can induce the changes of SOD activity and MDA content in rabbit lung tissue, and affect the expression of NOS and Ang ⅱ, suggesting that the mechanism of lung injury may be related to lipid peroxidation and NOS, Ang ⅱ abnormal expressio. 3. 高脂血症能够引起家兔肺组织内SOD活力、MDA含量的改变,并影响NOS和AngⅡ的表达,提示肺损伤的机制可能与脂质过氧化以及NOS、AngⅡ异常表达有关。