Conclusions Percutaneous biopsy with ultrasound guidance can be used briefly, safely and efficiently to diagnose omental lesions. It makes some patients with unknown etiogenic ascites and/ or abdominal distention get accurate diagnosis, and offers a remarkable help for clinical therapy. 结论超声引导经皮穿刺大网膜病变活检是一种简便、安全、有效、诊断准确性高的方法,可使一些不明原因的腹胀腹水患者获得明确的病理诊断,为临床治疗提供依据。