The consortium used ENU, a chemical that causes random mutations in sperm of mice that were subsequently mated with females. 该协会采用ENU,一种可导致小鼠精子随机突变的化学物质,突变后将雄性小鼠同雌性小鼠交配。
Using ENU mutagenesis we have identified a mouse model resembling human maple syrup urine disease. 突变鼠方面,已建立了一个与人类枫糖浆尿毒症相似的小鼠动物模式。
On neu ( enu) coordinate system 关于NEU(ENU)坐标系统
Objective In order to accumulate basis data on short-tail mutant mice induced using N-ethyl-N-nitrosourea ( ENU), their biological characteristics were studied. 目的研究ENU诱变手段获得的1种短尾突变小鼠的生物学特性,为相关研究提供基础数据资料。
Preliminary Study of Mice Mutation Induced by ENU 乙酰基亚硝基脲诱导小鼠突变的初步研究
The mutations induced by X-ray had higher average dominance than that of ENU-induced mutations, and the mutations that formed nonfunctional heterodimers had the highest dominance. X射线诱导的突变体较ENU诱导的突变体有较高的平均显性,形成无功能杂二聚体的突变体具有最高显性。
Conclusion The mouse models for human diseases could be obtained by ENU-induced mutation. 结论ENU为小鼠的强诱突变剂;通过诱变可以得到遗传突变小鼠,为建立人类疾病动物模型提供条件;
One day after plating, the cells were exposed for 2 h to various doses of ethylnitrosourea ( ENU). CAs and SCEs were examined by the standard methods, while CT was determined by cell counts. 接种细胞一天后,用不同剂量乙基亚硝基脲(ENU)处理2小时,然后用标准法检查其染色体畸变和SCE率,用细胞计数法测定细胞毒性。
ENU-induced Mutagenesis in Mice and Mapping and Cloning Several Mutation Genes ENU诱导小鼠突变及对部分突变基因的定位克隆
Studies on gene mutation and micronucleus formation induced by ethylnitrosourea ( ENU) in transgenic mice in vivo 乙基亚硝基脲诱发转基因小鼠体内基因突变及微核形成
The Heterozygous Effect of X-ray or ENU-induced Null-mutant Adh Alleles on Alcohol Tolerance of Drosophila melanogaster X射线和ENU诱变的Adh基因对黑腹果蝇醇耐受性的杂合效应
In this paper, two new scant hair mice were obtained by ENU inducing and mutant genes were mapped on chromosome. 本文即用ENU诱变获得了两例新的稀毛小鼠并对突变基因进行了染色体定位。本论文的工作由三部分组成。
The food intake of Bama miniature pigs may be significantly affected during the administration with ENU, the decrease in food intake was dose-dependent, and the recovery time for food intake increased with the increase in the dosage. ENU给药期间巴马香猪采食量会受到较大影响,采食量的减少具有浓度依赖性,采食量恢复时间随剂量的增加而延长。
ENU administration had no significant effects on the prostate of Bama miniature pigs. ENU给药对巴马香猪前列腺无明显影响。