Current studies indicate that the anticarcinogenic functions of CLA can be attributed to the ability to inhibit the synthesis of eicosanoids derived from arachidonic acid. 研究表明,共轭亚油酸的抗癌作用可归结为抑制衍生自花生四烯酸的类二十烷合成的能力。
Background Aims and Methods: Abnormal metabolism of eicosanoids is associated with pancreatic haemorrhage and necrosis in acute haemorrhagic-necrotizing pancreatitis ( AHNP). 重症胰腺炎(AHNP)胰组织出血、坏死被认为与二十碳烯酸类的异常代谢有关。
Role of eicosanoids on mesangial cell proliferation in mesangioproliferative nephritis 系膜增殖性肾炎中花生四烯酸产物对系膜细胞增殖的作用
Epidemiological, clinical, animal and laboratory studies have all provided evidence for prostaglandins and other eicosanoids in the tumorigenesis and growth. 流行病学、临床、动物及体外实验研究表明,二十烷酸(eicosanoid)代谢途径的产物在肿瘤的发生发展中起重要作用。
Role of eicosanoids on renal hemodynamics in nephrotoxic serum nephritis in rats 花生四烯酸氧化产物对肾毒性肾炎肾脏血液动力学的影响
For the metastatic foci, the abnormal metabolism of 18F-FDG was observed and CT, PET and PET-CT fusion images were obtained for accurate localization of these foci. exogenous PGE1 may influence the development of pancreatitis through regulating this abnormal metabolism of eicosanoids. 观察转移病灶18F-FDG的异常代谢情况,然后通过CT图像进行准确定位。结论二十碳烯酸的异常代谢参与了ANP的发生、发展,外源性PGE1通过干预这种异常代谢,影响胰腺炎的发展。
OBJECTIVE To investigate the effect of nitric oxide ( NO) on glomerular synthesis of eicosanoids in accelerated nephrotoxic serum nephritis ( NSN) in rats. 目的:探讨一氧化氮(NO)在实验性肾小球肾炎中对肾小球花生四烯酸(AA)产物合成的调节作用。