The stability of these triple helixes is so high that homopyrimidine PNA targeted to purine tracts of dsDNA invades the duplex by displacing one of the DNA strands. 这种三螺旋体的稳定性极高,以至于在同型嘧啶PNA靶向双链DNA嘌呤道时,能取代其中一条DNA链侵入双螺旋。
Penetration of IgG 3 Subtype of Anti-dsDNA Antibodies into Living Human Renal Mesangial Cells: New Mechanism for Renal Pathogenicity of Anti-DNA Antibodies IgG3型抗dsDNA抗体穿透人肾小球系膜细胞:狼疮肾炎发病机制新探讨
Theoretical Study for DNA and RNA on Their Stability Difference Relationship between Recurrent Abortion and dsDNA DNA和RNA双链稳定性差异的理论研究精子双链DNA与习惯性流产相关性研究
Manufacture of dsDNA Microarrays of DRE Cis-acting Element DRE顺式作用元件dsDNA芯片制备
Two-phase Flow Transportation Apply Practice of Coal Injection in Meishan Relationship between Recurrent Abortion and dsDNA 梅钢喷煤系统的双流相输送应用实践精子双链DNA与习惯性流产相关性研究
Relationship between Recurrent Abortion and dsDNA Rhoda is a chronic complainer. She is always dissatisfied. 精子双链DNA与习惯性流产相关性研究罗达的抱怨是习惯性的,她老是不满。
Deletion Assay of Exonuclease ⅲ Digesting Double-Stranded DNA; Relationship between Recurrent Abortion and dsDNA 核酸外切酶Ⅲ消化双链DNA的缺失测定精子双链DNA与习惯性流产相关性研究
Detection and Significance of Anti-nucleosome Antibodies and Anti-dsDNA Antibodies of Systematic Lupus Erythematosus in Children 儿童系统性红斑狼疮抗核小体抗体和抗dsDNA抗体的检测和意义
Conclusion Anti dsDNA autoantibodies have inhibitory effect on tumor cells via inducing apoptosis. 结果灭活肿瘤细胞免疫小鼠可诱导产生较高滴度的抗dsDNA自身抗体。结论AntidsDNA自身抗体具有抗肿瘤作用。
Objective: To investigate the specificity of the anti dsDNA antibodies in the sera of the patients with SLE. 目的:研究SLE患者血清中抗dsDNA抗体的结合特异性。
Objective To study the effect of different immunization methods on the production and pathogenicity of anti-dsDNA antibodies induced by kinetoplast DNA ( kDNA) derived from trypanosoma equiperdum ( TE) on normal mice. 目的研究不同免疫途径对马疫锥虫动基体DNA(kDNA)诱导正常小鼠产生抗双链DNA(dsDNA)抗体及其致病性的影响。
Objective: To discuss clinical value and characteristic of antinuclear antibody, anti-ENA antibodies and anti-dsDNA antibodies in lupus erythematosus. 目的:探讨抗核抗体(ANA)、抗ENA抗体和抗dsDNA抗体在红斑狼疮(SLE和DLE)的实际临床实用价值和特点。
The SAP/ DNA ratio was negative correlation with the anti dsDNA antibodies. SAP/DNA比值与抗DNA抗体水平呈负相关。
The Relativity Between the Level of Complement Anti-dsDNA and Systemic Lupus Erythematosus Activity 补体、抗dsDNA和系统性红斑狼疮活动的相关性
Detection of ANA, anti-ENA antibodies and anti-dsDNA antibodies in lupus erythematosus 红斑狼疮(SLE和DLE)抗核抗体、抗ENA抗体和抗dsDNA抗体的检测及意义
The SLEDAI score and anti-dsDNA antibody correlated positively, and complement components C3, C4 and leukocytes correlated negatively with serum concentration of IFN-α. IFN-α level correlated with the presence of fever and rash. 血清IFN-α水平与SLEDAI积分和抗dsDNA抗体水平呈正相关,与补体C3、C4和白细胞数量呈负相关:血清IFN-α水平与患者发热和面部红斑有关。
The purified protein was identified with SDS-PAGE and Western blot analysis and was used to cleave supercoiled dsDNA. 纯化蛋白经SDS-PAGE电泳与westernblot鉴定后,对pUC19质粒进行超螺旋dsDNA裂解研究。
Detection of anti-dsDNA antibody is helpful in the diagnosis and surveillance of SLE. 提示抗双链DNA的检测有助于SLE的诊断和病情监测。
The level of serum anti dsDNA antibodies was assayed by ELISA. ELISA法检测血清抗dsDNA抗体水平;
Bacteriophage lysins are lytic agents used by double-stranded DNA ( dsDNA) phages to coordinate bacterial cell wall lysis. 噬菌体裂解酶是双链DNA噬菌体所特有的细胞壁水解酶。
DsDNA ( double-stranded DNA) microarray, as a novel high-throughout technique, get a start in the field of DNA-binding protein research. It studied a dsDNA probe designing method for a new fabrication technology of the dsDNA microarray. dsDNA芯片(double-strandedDNAmicroarray)是用于DNA结合蛋白质表达研究的新技术,应用一种新的dsDNA芯片制作方法,研究了dsDNA探针设计,开发了相应的计算机模拟系统&DBP软件。
Methods Characteristics of renal biopsy and renal involvement of 46 systemic Lupus erythematosus patients with positive anti-dsDNA antibodies were compared to those of 37 SLE patients with negative anti-dsDNA antibodies. 方法比较46例抗dsDNA抗体阳性的系统性红斑狼疮患者与37例抗dsDNA抗体的系统性红斑狼疮患者之间的肾活检和肾损害特点。
The level of serum anti-nucleosomes antibody, anti-dsDNA antibody and anti-histone antibody were much higher than that of healthy controls. 抗核小体抗体水平、抗dsDNA抗体水平和抗组蛋白抗体水平均高于对照组。
Objective: To establish a chip technique to detect anti-dsDNA in the serum by using plasmid DNA as antigen, and compare it with ELISA. 目的:建立以质粒DNA作为抗原的检测血清中抗双链DNA(dsDNA)抗体的芯片方法,并与酶联免疫吸附实验比较,初步探讨用芯片法检测抗dsDNA抗体的临床价值。
Objective To investigate effects of anti dsDNA autoantibodies on growth of tumor in vitro and in vivo. 目的体内外探讨抗双链DNA(AntidsDNA)自身抗体对肿瘤生长的影响。
Methods The anti-dsDNA autoantibody was detected via ELISA from the sera of Balb/ c mice immunized with inactivated SP2/ 0 tumor cells. 方法以灭活SP2/0肿瘤细胞3次免疫Balb/c小鼠,末次免疫2周后采血,ELISA法检测血清中抗dsDNA自身抗体的表达水平。
Methods The levels of SAP and anti dsDNA antibodies were detected by enzyme linked immunosorbent assay ( ELISA). 方法用酶联免疫吸附测定(ELISA)方法检测SAP含量及抗dsDNA抗体,荧光分光光度法测定DNA水平。
The rate constants of chloroquine phosphate with dsDNA and ssDNA were estimated by fitting the real-time experimental data of capacitive sensor. 3. 通过拟合电容传感器实时响应实验数据,得到了磷酸氯喹与dsDNA和ssDNA的反应速率常数。
The effects mentioned above, it may work through dsDNA receptors DAI. 而上述这些作用,可能正是通过dsDNA的受体DAI发挥作用的。