Emodin inhibited ATP binding to Topoisomerase II to induce DNA double-strand breaks 大黄素通过抑制ATP与拓扑异构酶II的结合导致DNA产生双链断裂
Design Development of Double-strand Splitting Process for Ф 20mm Ribbed Steel Bar Ф20mm带肋钢筋双线切分工艺的设计开发
The influences of iNOS and NO changes on the double-strand DNA breaks ( DSB) were identified using ligation-mediated PCR. 通过连接反应介导的PCR(LM-PCR)方法,评价iNOS和NO水平变化对DNA双链断裂(DSB)的影响。
Objective To observe the consistency of DNA double-strand break between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis ( SCGE). 目的探讨整体照射与离体照射导致小鼠淋巴细胞DNA双链断裂的一致性,作为单细胞凝胶电泳技术应用于辐射生物剂量学的前期研究。
Packing of the chromatin fiber of meiotic chromosomes in two species of grasshoppers under SEM TEM Multiple double-strand helical structure 应用SEM和TEM研究两种蝗虫减数分裂染色体的染色质纤维的包装&多级双股螺旋结构
DNA single-and double-strand breaks of peripheral blood lymphocytes in mice induced by γ rays irradiation were detected by neutral and alkaline comet assay. 分别应用中性单细胞凝胶电泳、碱性单细胞凝胶电泳技术检测了不同剂量γ射线外照射对小鼠外周血淋巴细胞DNA的损伤。
DNA double-strand break induced by ionizing radiation 电离辐射诱导的DNA双链断裂
Rejoining fidelity of DNA double-strand breaks induced by restriction endonucleases in CHO cells 限制性内切酶诱发DNA双链断裂在细胞中的修复忠实性
PCNA was assayed by immunocytochemistry and DNA double-strand breaks were detected by TUNEL. 免疫组化法测定PCNA,TUNEL法检测DNA双链损伤。
The Experimental Study of the Treatment of the Decoy Double-strand Oligonucleotides for NF-kB in Rat Heart Transplantation NF-kB诱饵双链核苷酸在大鼠心脏移植中作用的实验研究
Detection of DNA double-strand break of lymphocytes as a biological marker in radiation injury 淋巴细胞DNA双链断裂用于放射损伤检测的可行性研究
Repair Inhibition of DNA Double-strand Breaks and Radiosensitization DNA双链断裂修复抑制与放射增敏
DNA becomes a candidate for molecular devices as its two of the most unique and appealing properties: double-strand recognition and self-assembly. 而DNA分子由于其独特的可识别性和自组装性成为制作分子器件的候选材料之一。
Several possible mechanisms have been presented to explain the mechanism of trans-gene silencing, such as RNA threshold, aberrant RNA and ectopic pairing model and double-strand RNA model. 人们目前用以下几种模型来解释转录后水平基因沉默的机制,如RNA阈值模型、异常RNA和异位配对模型及双链RNA模型。
This paper introduces the modification of slab caster from one-strand to double-strand casting and the effects of double-strand casting. 本文介绍承钢板坯连铸机由单流浇注改为双流浇注的改造,以及双流浇注改造的效果。
Comparison of Sensitivity to Heavy-Ion Induction of DNA Double-Strand Breaks between DNA and Intact Cells DNA和细胞对重离子辐照诱导DNA双链断裂的敏感性比较
CHAIN OF TESTS OF SERIES Conservation and Specificity of DNA Double-strand Break Repair in Plants 植物DNA双链断裂修复的保守性和特异性
Conclusion The result of neutral single cell gel electrophoresis shortly after in vitro irradiation can precisely reflect the DNA double-strand break of lymphocytes in whole-body irradiation. 结论离体血γ射线照后即刻进行中性单细胞凝胶电泳,可以客观准确地反映整体照射的淋巴细胞DNA双链断裂损伤。
A New Method for Calculating Yield of DNA Double-strand Breaks DNA双链断裂产额的新算法
These researches mainly include: clonogenic cell survival, chromosome damages and double-strand breaks of DNA. 这方面研究主要包括克隆细胞存活、细胞染色体畸变和细胞DNA损伤等。
The inhibiting mechanism of the antisense oligonucleotides on gene expression is as followed. ( 1) Inhibition of the gene transcription antisense oligonucleotides can bind to specific sequence of double-strand DNA and form triple-helical DNA to inhibit the transcription. 反义寡核苷酸对基因表达的抑制作用可通过多种不同机制而实现:①抑制基因转录,即反义寡核苷酸与DNA双螺旋分子的特定序列结合形成三螺旋DNA以阻止基因的转录。
Purpose: The DNA double-strand breaks ( DSB) and its repair ability of human tumor cell lines after irradiation were detected for studying the correlation to cell radiosensitivity. 目的:检测人类肿瘤细胞系统经X线照射产生的DNA双链断裂(DSB)及其修复过程,初步验证双链断裂及其修复与细胞放射敏感性的关系。
Deficiencies in cellular responses to DNA damage can predispose to cancer. Ionizing radiation can cause cluster damage and double-strand breaks ( DSBs) that pose problems for cellular repair processes. 细胞对DNA损伤反应缺陷会诱发肿瘤,电离辐射可引起DNA簇损伤和双链断裂,成为细胞修复过程的问题。
HIV-1 Tat Protein Inhibits Repair of Ionizing Radiation-Induced DNA Double-Strand Breaks and Increases Cellular Radiosensitivity HIV-1Tat蛋白抑制DNA修复和增强细胞辐射敏感性
The DNA double-strand in the biological system is complementary, in which a single strand contains all the genetic information. 生物体系中的DNA双链是互补的,其中单链上包含了有关的全部遗传信息,考察DNA双链结构中的电子转移行为可从研究其单链上的电子传递入手。
At present, the researches on DNA damage by means of Monte Carlo method are focused on single-strand breaks, double-strand breaks and corresponding clustered damages induced by direct and indirect inactions of radiation. 应用这一方法,目前国际上关于辐射诱导DNA损伤的研究主要集中在辐射的直接和间接作用引起单链断裂、双链断裂及其相应的簇损伤上。
Cu-I bond connect ( CuI) n chain to form double-strand ladder structure in complexes 1, 2. 在配合物1、2中Cu-I键将两条(CuI)n链连接形成梯形双链结构。
Determinants of tumor radiosensitivity are the intrinsic sensitivity of tumor cells, which affected by the cellular DNA double-strand break ( DSB) repair capacity. 肿瘤放射敏感性的决定因素是肿瘤细胞内在敏感性,而影响细胞内在敏感性的最重要因素是细胞DNA双链断裂(DSB)修复能力。
DNA double-strand breaks is a main formation of DNA damage. 双链DNA断裂是DNA损伤的主要形式。