Enzyme kinetics of dl-tetrahydropalmatine and corydalis extract metabolism in rat liver microsomes 延胡索乙素及延胡索提取物在大鼠肝微粒体内代谢动力学研究
Methods: using orthogonal design method, to apply extract yield of Rhizoma Coptis and the extract amount of berberine hydrochloride as observing indexes, to measure the content of dl-tetrahydropalmatine with hplc. 方法:采用正交设计法,以槲皮素、原儿茶醛薄层斑点,延胡索乙素含量为指标,优选提取工艺。
OBJECTIVE To study the enantiomeric separation of two tetrahydroprotoberines ( dl-tetrahydropalmatine and dl-tetrahydrobeberine) on two chiral columns based on alpha acid glycoprotein ( AGP) and cellulose tris ( 4-methylbenzoate) by HPLC. 目的在α-酸性糖蛋白手性柱和纤维素-三(4-甲基苯甲酸酯)手性柱上,对两种四氢原小檗碱同类物(延胡索乙素和四氢小檗碱)进行了对映体分离研究。
Protective Effects of dl-tetrahydropalmatine on Experimental Myocardial Necrosis by Isoprenaline in Rat 延胡索乙素对异丙肾上腺素所致心肌坏死的保护作用
To study the protective effect of ( dl-tetrahydropalmatine dl-THP) on experiment myocardial necrosis in rats. 目的:研究延胡索乙素(dl-THP)对应激状态下心肌缺血坏死的保护作用。
Effect of dl-tetrahydropalmatine on rat gastric ulcer dl-四氢巴马汀抗大鼠胃溃疡作用
Dl-Tetrahydropalmatine ( THP), a short-term monoamine depletor, has been found to be able to decrease the firing rate of the neurons in the nucleus accumbens ( A). dl-四氢巴马汀(THP)能使大鼠伏核神经元的自发放电明显下降。
Effects of dl-tetrahydropalmatine on cardiac hemodynamics in dogs DL-四氢巴马汀对犬心脏血流动力学作用
Calcium antagonistic effect of dl-tetrahydropalmatine on isolated rat uterus dl&四氢巴马汀在子宫平滑肌上的钙拮抗作用
Effects of dl-tetrahydropalmatine on the slow response action potentials in rabbit sinoatrial node and guinea pig papillary muscle dl-四氢巴马汀对家兔窦房结和豚鼠心室肌慢反应电活动的影响
Depletion of monoamines in the rat by dl-tetrahydropalmatine DL-四氢巴马汀对大鼠单胺的排空作用
[ Objective] To observe the in vivo effects of dl-tetrahydropalmatine given by intravenous injection on electrocardiogram and His electrograph in rabbits, further to explore its action on cardiac conduction system. [目的]观察消旋四氢巴马汀静脉注射对在体家兔心电图和希氏束电图的影响,以探讨消旋四氢巴马汀对家兔心脏传导系统的作用。
OBJECTIVE To study the effect of dl-tetrahydropalmatine ( dl-THP) on various rat gastric ulcers and analyze its possible mechanism. 目的研究dl-四氢巴马汀(dl-THP)对大鼠急、慢性溃疡的保护作用,并初步分析其机制。方法胃黏膜损伤由吲哚美辛、束缚应激、结扎幽门和胃浆膜下注入醋酸引起。
Objective: To study the effect of dl-tetrahydropalmatine ( dl-THP) on pulmonary arterial vascular remodeling induced by chronic hypoxic hypercapnia in rats and explore its mechanism. 目的研究延胡索乙素(dl-THP)对慢性低O2高CO2性肺动脉高压大鼠血管重构的影响及其机理。
The effect of dl-tetrahydropalmatine on pulmonary arterial vascular remodeling induced by chronic hypoxic hypercapnia in rats 延胡索乙素对低O2高CO2肺动脉高压大鼠c-jun、c-fos表达的影响