dephosphorylation
英
美
n. 脱磷酸（作用）
双语例句
- The mechanism of action was proved to be reversible phosphorylation and dephosphorylation.
其作用机理亦是通过可逆的磷酸化及脱磷酸化作用进行的。 - It is demonstrated that phosphorylation and dephosphorylation of NRs play a critical role in a variety of signaling pathways.
研究表明，核受体的磷酸化与去磷酸化在多条信号途径中起着重要作用。 - Non-NMDA receptors is a general designation of AMPA receptors and KA receptors. Many phosphorylation and dephosphorylation sites as well as the intracellular proteins-binding sites are existed on the C-terminal of the non-NMDA receptor subunits, which are closely related to the modulation of the non-NMDA receptors.
非NMDA受体是AMPA受体和KA受体的统称，其亚基上的胞内C末端上有很多磷酸化脱磷酸化及胞内蛋白的结合位点，这些作用位点与非NMDA受体的调控密切相关。 - The mechanism of effect of Acanthopanax senticosus on liver microsomal HMG-CoA reductase and 7 α-hydroxylase was proved to be reversible phosphorylation and dephosphorylation via corresponding kinase and protein phosphatase.
刺五加水煎液对肝微粒体羟甲基戊二酰辅酶A还原酶和胆固醇7α-羟化酶活力调节作用是通过可逆的磷酸化及脱磷酸化作用而实现的。 - Effect of Protease Digestion and Dephosphorylation on High Emulsifying Properties of Hen Egg Yolk Phosvitin
卵黄高磷蛋白酶解和脱磷对乳化性的影响研究 - Novel phosvitin phosphopeptides ( PPP) were prepared by tryptic hydrolysis following alkaline dephosphorylation of hen egg yolk phosvitin.
以卵黄高磷蛋白质为原料，经碱法脱磷、胰蛋白酶水解后分离制备得到一种新型的卵黄高磷蛋白磷酸肽（PPP）。 - The post receptor signal transduction consists of a series of receptor associated tyrosine protein kinase activated intracellular protein phosphorylation and dephosphorylation reactions, such as the phosphorylation of insulin receptor substrate 1 ( IRS 1), Shc, Ras and phosphatidylinositol 3 kinase ( PI3 K).
受体后的信号转导经过了一系列磷酸化和去磷酸化等途径，其中有胰岛素受体底物1（IRS1）、Shc蛋白、Ras蛋白以及磷酸肌醇3激酶（PI3K）等的参与。 - Changes in Tyrosine Protein Phosphorylation and Dephosphorylation in ts-RSV LA-90 Cells Transformation
LA－90细胞在温度转化过程中蛋白质酪氨酸磷酸化作用研究 - Under the regulation of the kinetics of the phosphorylation dephosphorylation cycle in hepatocytes by Ca 2+ oscillations, the concentration of glycogen phosphorylase oscillated synchronously.
肝细胞中的磷酸化去磷酸化动力学过程，在Ca2+振荡的调控下，其糖原磷酸化酶的浓度呈现同频、同步振荡。 - The dephosphorylation of FAK;
FAK去磷酸化； - β-catenin could also regulate its activity and quantity by phosphorylation of the tyrosine residues and dephosphorylation, and it plays im-portant roles in the regulation of proliferation of enteric stem cells and the differentiation and migration of daughter cells.
β-连环蛋白还可通过酪氨酸残基的磷酸化与云磷酸化实现其活性和量的调节，并且在调控肠干细胞增殖及其子代细胞的分化、迁移过程中起着重要的作用。 - GA decreases the nitrate reductase activity but increases the nitrate content in roots, and promotes the dephosphorylation of the enzyme;
GA降低根中硝酸还原酶活性但提高硝酸根含量，提高该酶的去磷酸化水平； - 2.1 IBA decreases both the nitrate reductase activity and nitrate in roots and leaves, and promotes the dephosphorylation of the nitrate reductase and the sucrose content.
2.1IBA降低根和叶的硝酸还原酶活性及硝酸根含量，提高揖和叶中该酶的去磷酸化水平及蔗糖含量。 - Protein phosphorylation and dephosphorylation are the general means of regulation metabolism within a cell.
蛋白质的磷酸化与脱磷酸化是生物体内存在的一种普遍的调节方式，几乎参与所有的生命活动过程。 - Protein phosphorylation is one of the most important reversible post-translational modifications ( PTMs). Phosphorylation and dephosphorylation provides a regulatory mechanism in eukaryotic cells.
磷酸化是最重要的蛋白质翻译后修饰之一，蛋白质磷酸化和去磷酸化为真核细胞提供了调节机制。 - Effect of Dephosphorylation on the Structure and Function of Alzheimer Neurofibrillary Tangles
去磷酸化对Alzheimer神经原纤维缠结结构和功能的影响 - The expression of HER-2 up-regulation and SHP-1 down-regulation damage balance of phosphorylation and dephosphorylation, then excessive activation of phosphorylated signal ultimately enhance the degree of malignance and invasion of the cells.
HER-2表达升高和SHP-1表达下降，导致蛋白磷酸化及去磷酸化平衡破坏，磷酸化信号过度活化，细胞恶性程度及侵袭能力增加。 - As a modified protein, there are two forms-phosphorylation and dephosphorylation in Rb protein, and its active form is dephosphorylation.
Rb蛋白作为一种修饰蛋白，有磷酸化和去磷酸化两种形式，去磷酸化为其活性形式。 - The latter includes phosphorylation, dephosphorylation, acetylation, ubiquitination and modulation by interacting proteins.
后者包括磷酸化与去磷酸化、乙酰化、泛素化和被相互作用蛋白调控等。 - Correspondant with the existence of phosphorylation, dephosphorylation also plays an important role in the cell cycle regulation.
与磷酸化相对应存在，去磷酸化修饰在细胞周期中同样起着重要的调控作用，共同构成了磷酸化和去磷酸化这一重要的蛋白质活性的开关系统。 - Protein kinases and protein phosphatases catalyze the reversible protein phosphorylation and dephosphorylation as two kinds of key enzymes.
蛋白激酶和蛋白磷酸酶是催化可逆性蛋白磷酸化和脱磷酸的2种关键酶类。 - Conclusion Metformin can inhibit proliferation of osteosarcoma cells in vitro, which is associated with the dephosphorylation of Akt/ FoxO1signal pathway.
结论二甲双胍可通过Akt/FoxO1信号通路的去磷酸化而抑制MG63细胞的增殖。 - This confirms that the processive phosphorylation is an important mechanism of protein phosphorylation and dephosphorylation in MAPK signal transduction pathway.
说明过程型作用机制也是MAPK信号通路中蛋白质磷酸化与去磷酸化的一种重要的作用机制。 - Reversible protein phosphorylation/ dephosphorylation modifications play a key role in extracellular signaling pathways.
蛋白质的可逆磷酸化和去磷酸化修饰在将细胞外信号传递入细胞内及细胞内信号传递途径中起到了关键性作用。 - Protein phosphorylation and dephosphorylation, which are mainly done by protein kinases and phosphatases, two kinds of enzymes possessing converse functions, are most important aspects of signal transduction pathways in all kinds of organisms.
蛋白质磷酸化与去磷酸化是细胞信号转导的重要过程，主要通过蛋白激酶和蛋白磷酸酶来完成。 - Protein phosphatase catalyzed dephosphorylation reaction, so that protein phosphorylation and dephosphorylation, terminate the transfer of signaling molecules, and thereby regulate cell signaling signal transduction pathway.
蛋白磷酸酶与蛋白激酶作为一对开关调控细胞内的一系列生化反应，蛋白磷酸酶可以催化去磷酸化反应，使磷酸化的蛋白质脱磷酸化，终止信号分子的传递，从而调控细胞信号转导通路。 - Combined with our previous work, we concluded that dephosphorylation of SHP-1 may reverse the excessive activation of the signaling pathway.
综合我们前期工作，我们可以推断SHP-1的去磷酸化作用可使肿瘤细胞逆转其信号通路的过度激活。 - PP1 is composed of catalytic subunits and regulatory subunits, which modulates metabolism, cell differentiation and signal transduction by dephosphorylation. The regulatory subunits determine the substrate specificity, activity and subcellular localization of PP1.
Ⅰ型蛋白磷酸酶（PP1），通过去磷酸化蛋白调节机体代谢、细胞分化以及信号转导等。它由催化亚基和调节亚基组成，后者决定磷酸酶的底物特异性，活性以及亚细胞定位。 - The important negative regulatory role of SHP-1 mainly affected the dephosphorylation of growth factor receptors or non-receptors protein tyrosine kinase.
SHP-1主要通过对生长因子受体或非受体蛋白酪氨酸激酶的脱磷酸作用起着重要的负性调节作用。