The inhibition of deoxynucleoside metabolism is one possibility. 脱氧核苷代谢的抑制是一种可能性。
Methods In the presence of trimethylsilyl trifluoromethane-sulfonate ( TMSOTf), condensation of 3 ′-O-( diphenylphosphinyloxy) methyl acetal ( 1) with 3 ′-protected deoxynucleoside ( 2 or 6) afforded dimers ( 3) or trimers ( 7) respectively. 方法3′O(二苯膦酰氧)甲基缩醛核苷(1)在三甲基硅三氟甲磺酸酯(TMSOTf)条件下,与3′位保护的脱氧核苷(2或6)缩合。
The determination of the K m value for other nucleosides and deoxynucleoside indicated that the nucleoside specificity of this enzyme from yeast was quite high. 该酶对其他核苷和脱氧核苷的Km值测定数据表明,从酵母中克隆得到的该重组腺苷激酶具有较高的底物特异性。
Objective: To investigate and compare the effects of deoxynucleoside triphosphates ( dNTP) on human lymphocytes and plant root tip cells SCE. 目的:研究和比较4种三磷酸脱氧核苷(dNTP)对人外周血淋巴细胞和植物根尖细胞姐妹染色单体交换(SCE)的影响,探讨其发生的机理。