HID4 recognizes another antigenic determinant and cross-reacts with fibrinogen degradation products X, Y and D fragments. HID4则识别另一抗原决定簇,且与纤维蛋白原碎片X、Y、D等有交叉反应。
These results suggest glomeruli contain the antigen that cross-reacts with the antibody homologous to the Tub-Ag present in the brush border of tubule epithelium, and confirm the significance of the in situ formation of immune complex in the pathogenesis of PHN. 提示:肾小球中含有与肾小管刷状缘上Tub-Ag起交叉反应的抗原;PHN的发病机制确为IC原位形成所致。
Conclusion: Although production of myosin-reactive Abs is not prerequisite for induction of MG, for myosin cross-reacts with AChR, myosin-Ab may play an important role in the pathogenesis of MG. 结论:Myosin-Ab虽然不是诱发MG的必要条件,但由于myosin与AChR存在抗原交叉性,myosin-Ab在MG的发病机制中可能起重要作用。