clofibrate

1. Objective To explore the effect of clofibrate on freshly isolated mouse liver mitochondria and a cultured hepatocyte cell line, AML-12.
   目的研究氯贝丁酯对离体小鼠肝线粒体和体外培养的AML-12肝细胞损伤的作用机制。
2. Treatment of hepatocytes with clofibrate caused a significant increase in intracellular and mitochondrial ROS.
   用氯贝丁酯处理过的肝细胞及线粒体内自由基显著增加。
3. AS to the action of clofibrate on HDL sub-fraction, we found that it was HDL2-C but not HDL3-C that was mainly affected.
   进一步观察表明，安妥明对高密度脂蛋白亚组份的作用是使HDL2-C升高，而对HDL3-C无明显影响。
4. AIM To study the relationship between hepatomegaly and change of plasma HGF level induced by clofibrate in rats.
   目的研究氯苯丁酯引起的大鼠肝脏肿大与血浆中HGF水平变化的关系。
5. A study of structure-effect relationship of clofibrate and its homologue
   安妥明及其同系物构效关系研究
6. Effects of phenobarbital and clofibrate on the detoxification of soman in mice
   苯巴比妥及氯贝丁酯对小鼠体内梭曼解毒作用的影响
7. The induction of phenobarbital and clofibrate, which are liver microsomal inducers, on organophosphate detoxifying enzymes, and the effect of these two medicines on the disappearance of soman from blood in mice were investigated.
   考察了肝微粒体酶诱导剂苯巴比妥及氯贝丁酯对小鼠体内解毒酶的诱导作用及对小鼠体内梭曼解毒作用的影响。
8. In this study, the metabolic stability of commonly used fibrates ( gemfibrozil, clofibrate, fenofibrate, bezafibrate) were investigated using rat and human liver microsomes.
   本课题研究了经常使用的几个贝特类药物（吉非罗奇、氯贝特、菲诺贝特、本扎贝特）在大鼠和人的肝微粒体中的代谢稳定性。

noun

1. a drug (trade name Atromid-S) that reduces lipids in the blood serum

   Synonym:    Atromid-S