cftr

1. Identification and Characterization of CFTR Chloride Channel Activators from Antihypertensive Traditional Chinese Medicine
   降压作用传统中药中CFTR-C1~-通道激活剂的筛选及性质鉴定
2. The researchers used gene targeting to disrupt one copy of the normal CFTR gene in pig cells.
   研究者通过基因靶向措施干扰猪细胞中正常的CFTR基因拷贝。
3. Newborn pigs lacking CFTR showed defective chloride transport and developed meconium ileus, exocrine pancreatic destruction, and focal biliary cirrhosis, which are all hallmark of CF disease.
   新生的缺乏CFTR基因的猪表现出氯化物转移缺陷，胎粪性肠梗阻，胰腺外分泌缺陷和局限性胆道硬化，而这些症状正是人类CF疾病的主要症状。
4. Researchers Erich Gulbins, MD, PhD, of Germany's University of Duisburg-Essen and colleagues now find that CFTR dysfunction upsets a delicate chemical balance in the lungs.
   现在，德国Duisburg-Essen大学研究人员ErichGulbins博士和他的同仁们发现CFTR的异常扰乱了肺部精细的化学物质平衡。
5. In individuals with cystic fibrosis, the CFTR protein is mutated, often with one or more amino acids deleted, and consequently misfolded.
   囊性纤维化者CFTR蛋白变异，通常出现一个或更多的氨基酸缺失并因此错误折叠。
6. Although it is known that mutations in the CFTR gene cause the disease, variations in other genes between individuals with CF modify the severity of the disease.
   虽然，囊性纤维跨膜通道调节因子基因（CFTR）突变是这种疾病的病因，但在患有CF的病人之间的不同基因的变异会改变这种疾病的严重度。
7. The Gating Function of CFTR on Human Bronchial Epithelial Cells under Oxidant Stress and Its Regulation Mechanism
   氧化应激对支气管上皮细胞CFTR门控功能及调控机制研究
8. CFTR polymorphisms of healthy individuals in Chinese-the comparison between populations in Changchun and Nanjing regions
   中国健康人群CFTR基因多态性研究-长春和南京两个地区人群的比较
9. CFTR Chloride Channel Activator Screening and Molecular Pharmacology Researching
   CFTR氯离子通道激活剂的筛选及其分子药理学机制研究
10. Loss of CFTR proteins stops water from flowing into or out of the cells, thereby altering the conditions in the airway, leading to cystic fibrosis.
    CFTR蛋白缺乏使水分不能自由出入细胞，因而改变了气道环境，导致囊性纤维化。
11. Intein-mediated Trans-splicing of Chloride Ion Channel CFTR
    内含肽介导的氯离子通道蛋白CFTR的反式剪接
12. The etiology of CAVD is associated with the cystic fibrosis transmembrane conductance regulator ( CFTR) gene and defects in the Wolffian duct, and frequently complicated by renal agenesis and other urogenital abnormalities.
    研究表明，CAVD的发病与囊性纤维化跨膜转运调节物（CFTR）基因突变和中肾管发育缺陷有关。CAVD患者可合并肾发育不全和其他泌尿系统异常。
13. Advances in relationship between cystic fibrosis transmembrane conductance regulator gene and the pathogenesis of nasal polyp
    CFTR基因在鼻息肉发病机制中的研究进展
14. CFTR mutations have no effect on results of ICSI in congenital obstructive azoospermia patients
    CFTR突变基因不影响先天性梗阻性无精子症患者ICSI治疗的成功率
15. A Study on Gallbladder Motility and Expression of CFTR mRNA in Cholesterol Gallstone Patients
    胆囊壁CFTRmRNA表达与胆囊动力学关系的研究
16. The necessity of complete CFTR mutational analysis of an infertile couple before in vitro fertilization
    不孕症夫妇体外受精前进行完整的囊性纤维化病跨膜调节因子基因突变分析的必要性
17. Result: ① CFTR was detected in the two tissues and localized mainly in epithelial cells and secretory cells.
    结果：①CFTR在上述2组组织均有表达，主要表达于上皮细胞和分泌细胞，并且优势表达于鼻息肉。
18. CFTR and cystic fibrosis
    CFTR与囊性纤维化
19. The cystic fibrosis transmembrane conductance regulator ( CFTR) is a cAMP-activated and ATP-gated Cl~-channel expressed in the apical plasma membrane of epithelial cells in the airways, digestive and reproductive tracts.
    囊性纤维化跨膜传导调节因子（CFTR）是一种cAMP激活的ATP门控性氯离子通道，表达于气道，消化道和生殖道上皮细胞的顶部质膜中。
20. Since the discovery of CFTR gene, more than 1,200 mutations have been identified. The frequency and hot spots of CFTR gene mutation vary with race and nation.
    CFTR基因有高度多态性，目前已报道有12C0多种突变形式，而且CFTR基因突变频率及热点依民族、种族及地理位置不同而有差异。
21. Study of CFTR Gene Mutations and Testicular Ultrastructure and ICSI of Congenital Obstructive Azoospermia
    先天性梗阻性无精子症患者CFTR基因突变及其睾丸超微结构的研究和ICSI治疗的临床观察
22. Recent study manifested that CFTR is also expressed in smooth muscle of blood vessel.
    最新研究发现，CFTR还在血管平滑肌上表达，对机体血压调节具有重要意义。

noun

1. the gene that is mutated in cystic fibrosis

   Synonym:    cystic fibrosis transport regulator