Amikacin ( AMK) in the serum of healthy volunteers was determined by the improved microbiological method and was compared with combination of AMK and cefazolin ( CEZ). 采用微量微生物法对阿米卡星(AMK)单用及AMK与头孢唑林(CEZ)合用后,健康者体内AMK血药浓度进行测定;
Methods: The serum concentration of cefazolin and plasma protein binding rate in neijiang pig was detected by high performance capillary electrophoresis. 方法:选择主要经肾脏排泄的CEZ为模型药,采用高效毛细管电泳法测定其血药浓度,并计算药代动力学参数;采用平衡透析法测定其血浆蛋白结合率。
Antimicrobial activity of cefazolin ( CEZ) combined with a beta-lactamase inhibitor sulbactam ( SBT) against beta-lactamase producing strains of clinical isolates was studied in vitro using liquid dilution method compared with cefazolin alone. 用液体培养基试管二倍稀释法测定头孢唑林联合舒巴坦对常见临床分离产酶菌的最低抑菌浓度(MIC),并与头孢唑林进行比较。
Cefazolin sodium ( CEZ) is one of the first generation cephalosporins. 头孢唑林钠是第一代头孢类抗生素。