caspases
英
美
网络 半胱天冬氨酸蛋白酶; 半胱氨酸天冬氨酸蛋白酶; 半胱氨酸蛋白酶; 凋亡酶; 凋亡蛋白酶
双语例句
- Ye says, adding that follow-up work allowed them to set aside caspases as suspects and focus on AEP.
因为随后的工作让他们隔离了猜想中的半胱天冬酶而得以专注于AEP（的研究）。 - Objective To explore the relationship between the apoptosis of cerebellar granule cell and the changes of caspases-3 and Bcl-2 in rats with methylmercury intoxication.
目的探讨大鼠汞中毒时小脑颗粒层细胞凋亡与半胱氨酸蛋白酶（caspases）3及Bcl2的关系。 - Norcantharidin induces HeLa cells apoptosis through caspases pathway
去甲斑蝥素通过半胱氨酸天冬氨酸酶诱导HeLa细胞凋亡 - Natural inhibitors of caspases and cell apoptosis
半胱天冬酶天然抑制剂与细胞凋亡 - Therefore, cardiac myocytes apoptosis induced by hypoxia are the result of multi-factors interaction. Many factors, such as Bcl-2 family proteins, mitochondrial permeability transition, cytochrome c release and caspases activation, are involved in hypoxic cardiomyocytes apoptotic regulation.
因此，低氧时心肌细胞凋亡的产生是多种因素综合作用的结果，Bcl-2家族蛋白、线粒体通透性改变、细胞色素c的释放以及caspases的活化等参与了低氧引起的心肌细胞凋亡的调控。 - OBJECTIVE: To investigate the effect on Caspases expression in PGCl_3 cells for studying mechanism of apoptosis of PGCl_3 cells induced by death associated protein kinase ( DAPK).
目的：探讨死亡相关蛋白激酶（Deathassociatedproteinkinase，DAPK）诱导PGCl3细胞凋亡的可能机制及其对半胱氨酸蛋白酶（Caspases）表达的影响。 - Effect of activation of caspases in apoptosis induced by camptothecin in bladder cancer cell
天冬氨酸特异性半胱氨酸蛋白酶活化在喜树碱诱导膀胱癌细胞凋亡中的作用 - Caspases are a family of cysteine requiring aspartate proteases with sequence similarity to Ced-3 protein of Caenorhabditis elegans.
Caspases家族与秀丽隐杆线虫Ced-3蛋白具有相似的半胱天冬酶序列。 - Effects of Fas, NF-κ B and caspases on microvascular endothelial cell apoptosis induced by TNF α
Fas、NF-κB及Caspases在TNFα介导的微血管内皮细胞凋亡中的作用 - The caspase inhibitor has a neuroprotective effect, which can inhibit the activity of caspases, block the caspase-mediated apoptotic pathways, and may open a new way for the treatment of the neurologic diseases.
Caspase抑制剂能抑制caspase活性，阻断caspase介导的细胞凋亡途径，具有神经保护作用，有可能为这些疾病的治疗开辟新的途径。 - Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases
三氧化二砷通过激活Caspases酶诱导髓性白血病细胞凋亡 - Caspase-2 is one special member of Caspases family. It shows structure and function similarity to both initiator Caspases and effector Caspases.
Caspase-2是Caspase家族中的一个特殊成员，具有类似于启始Caspases与效应Caspases的结构与功能特征。 - This pathway including several processes such as cell membrane phosphatidylserine translocation, intracellular reactive oxygen species level increase, mitochondria dysfunction, cytochrome c release, caspases activation and so on.
线粒体凋亡途径包括细胞膜磷脂酰丝氨酸翻转、胞内活性氧水平升高、线粒体功能障碍、释放细胞色素c、激活半胱氨酸蛋白酶等环节。 - There are four pathways involved in skeletal muscle consumption/ wasting: ATP-dependent ubiquitin-proteasome pathway, caspases pathway, lysosomal pathway and calpain pathway.
参与骨骼肌消耗/萎缩的途径主要有有四条：依赖ATP的泛素-蛋白酶体途径、caspases途径、溶酶体途径和Ca2+依赖蛋白酶途径。 - Once caspases are activated, they cleave substrate proteins, which will ultimately lead to the morphological manifestations of apoptosis, such as membrane blebbing, and DNA condensation and fragmentation.
一旦凋亡酶被激活，它们将裂解蛋白质底物分子，导致DNA凝聚、断裂和胞膜出芽等细胞凋亡的形态学改变。 - The structure changes of apoptotic cells are mainly induced by Caspases. Once these intracellular enzymes are activated, cells enter apoptotic process.
凋亡细胞的形态变化大多由胱天蛋白酶系（Caspases）引发，一旦胞内的这些酶被特异性激活，细胞即进入凋亡。 - Calcium ion concentration increased, decreased mitochondrial membrane potential will lead to increased mitochondrial Ca2+ uptake, mitochondrial calcium overload leading to mitochondrial damage, cyt-c release, activation of caspases, ultimately leading to apoptosis.
钙离子浓度升高、线粒体膜电位的下降将导致线粒体钙超载，导致线粒体损伤，使线粒体跨膜电位下降，进而引起cyt-c释放，caspases活化，最终导致细胞凋亡。