RESULTS: The expression of AFP and Ha-ras, c-myc genes in the cultured oval cells from different phases was synchronous: At the beginning of oval cell cultivation in vitro, both of AFP and oncogenes displayed a higher level expression and then declined. 结果:AFP及c-ras、c-myc在卵圆细胞体外培养的不同时期呈现同步升高或降低:培养初期,卵圆细胞AFP及癌基因均呈高表达,而后下降;
Expression of bcl-2, C-ras p21 and PCNA in ovarian epithelial cystadenoma Bcl-2、C-rasp21和PCNA在卵巢上皮性囊腺肿瘤的表达及意义
Localization of c-ras~ h oncogene on human chromosome by in situ hybridization 染色体原位杂交技术的应用C-ras~H癌基因的定位研究
Relationship between c-ras and progesterone production in cultured rat granulosa and luteal cells c-ras与大鼠颗粒细胞和黄体细胞生成孕酮的关系
AIM: To study the effects of oncogenes on differentiation and transformation of oval cells by detecting and characterizing the expression of AFP and Ha-ras, c-myc genes of rat oval cells in vitro. 目的:通过对体外培养的大鼠卵圆细胞进行AFP和c-ras、c-myc基因的动态测定,观察二者在卵圆细胞转化过程中的变化特点,探讨癌基因对细胞分化和转化的影响。