How do you differentiate between bronchoconstriction from asthma and anaphylaxis? 如何鉴别哮喘的支气管收缩和过敏反应?
Methods Investigated the effect on LTD4 and spasmogen ( histamine)-induced airway microvascular leakage and bronchoconstriction. 方法通过整体实验,研究样品对白三烯D4(LTD4)引起的微血管渗漏,LTD4、组胺引起支气管收缩的影响。
Removing the influence of bronchodilation, atropine revealed marked suppression to IHV induced bronchoconstriction ( P < 0.01). 排除阿托品吸入后支气管扩张作用的影响,其对IHV诱发的支气管收缩有明显的抑制作用(P<0.01)。
Objective To investigate the effects of endothelin antagonist, Bosentan on bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs and to explore the effect of endothelin in the pathogenesis of exercise induced asthma ( E1A). 目的通过内皮素(ET)受体非肽类拮抗剂Bosentan对豚鼠等CO2过度通气模型影响的观察,探讨运动性哮喘的发病机制以及ET受体拮抗剂的治疗作用。
The effect of montelukast, a leukotriene antagonist, on improvement of exercise-induced bronchoconstriction 孟鲁司特钠治疗运动诱发性支气管收缩的临床研究
Effect of Adrenomedullin on bronchoconstriction responses induced by histamine 肾上腺髓质素对组胺诱发气道痉挛的作用
Conclusion Zafirlukast has definite treating effect on exercise-induced bronchoconstriction in children. 结论扎鲁司特对儿童运动性哮喘有较好的治疗作用。
Conclusion Loratadine and ketotifen can inhibit the exercise-induced bronchoconstriction in guinea pigs pretreated with LPS and metyrapone. 结论在用脂多糖和甲吡丙酮预处理的运动性哮喘豚鼠模型中,氯雷他定和酮替芬能够抑制支气管收缩。
Conclusions The study demonstrates a dissociation between the bronchoconstrictor response and bronchial hyper-responsiveness and indicates that multiple ovalbumin exposures induces persistent bronchoconstriction with airway hypo-responsiveness despite airway allergic inflammation. 结论本研究证实反复过敏原激发后支气管收缩反应和气道高反应性不存在相关性,同时提示反复过敏原激发后虽然出现过敏性气道炎症,但气道反应性降低伴持续支气管收缩反应。
Children have the highest prevalence of asthma, an obstructive lung disease characterized by bronchoconstriction, persistent airway inflammation and airway remodeling. 哮喘是一种梗阻性肺疾病,以支气管收缩、持续性气道炎症和气道重塑为特征。
Objective: To investigate the effect of Nitric Oxide ( NO) as a bronchodilator on releasing bronchoconstriction and improving pulmonary gas exchange through the experimental research, and investigate the effect of inhaling NO and Helium Oxygen mixture ( Heliox) simultaneously on asthmatic dogs. 本研究的目的即通过动物实验,观察一氧化氮作为支气管扩张剂解除气道痉挛的作用及对肺内气体交换的影响,以及同时吸入一氧化氮和氦氧混合气对哮喘的作用。
Methods: 12 male mangles were included in this study. The bronchoconstriction was induced by intratracheal infusion of methacholine. 方法:选取12只雄性杂种犬采用交叉设计、自身对照的方法进行实验,采用向气管内注入乙酰甲胆碱的方法使气道平滑肌痉挛。
TXA_2 receptor antagonist ( AA-2414) can inhibit bronchoconstriction induced by PAF with platelet significantly. 血栓素A2受体拮抗剂(AA-2414)明显抑制了PAF加血小板而引起的支气管平滑肌收缩。
Excessive bronchoconstriction occurred in one patient ( 1/ 41, 2.44%). 有1例患者气道出现过度收缩,发生率为244%(141)。
Platelet-activating factor induced bronchoconstriction and possible mechanisms 血小板活化因子的支气管收缩作用及其机理研究
Objective To study the efficacy of montelukast, a cysteinyl leukotriene receptor antagonist, in the treatment and prevention of exercise-induced bronchoconstriction ( EIB) in mild asthmatic patients and patients with exercise-induced asthma ( EIA). 目的观察孟鲁司特钠治疗轻、中度支气管哮喘(简称哮喘)并发运动诱发支气管收缩(EIB)或运动性哮喘(EIA)的治疗及预防作用。
Effects of tachykinin receptor antagonists on leukotriene C 4 induced bronchoconstriction and airway microvascular leakage in guinea pigs 1 速激肽受体拮抗剂对白三烯C4诱导豚鼠气道收缩和微血管渗漏的作用
To explore the security of fibrobronchoscope-induced test in isolated lung segment and the security of bronchoconstriction reaction conducted by hypertonic saline, meanwhile, collect alveolar lavage to measure correlative cytokine. 目的探讨支气管镜介导的肺段内隔绝激发试验的安全性及高渗盐激发的支气管收缩反应,同时收集肺泡灌洗液作相关细胞因子测定。
AIM: The mistaken suck can induce the reflectivity bronchoconstriction, make blood oxygen saturation decrease, so the deglutition function in patients with stroke can be reflected with the measurement of blood and oxygen saturation beside bed. 目的:误吸可致反射性的支气管收缩,使血氧饱和度下降,故利用床旁血氧饱和度测定可反映脑卒中患者的吞咽功能。
Effect of atropine on bronchoconstriction induced by isocapnic hyper-ventilation in asthma 阿托品对等二氧化碳过度通气诱发支气管收缩的影响
The inhibitory effect of EM-1 on the EFS-induced bronchoconstriction was stronger than that of the same dose of morphine as well as the five EM-1 derived peptides at the same frequency. 在相同频率刺激时,EM-1的抑制作用强于等浓度的吗啡和五个衍生多肽。
M3 muscarinic receptors are localized on inflammatory cells, airway smooth muscle, and submucosal glands, known to mediate bronchoconstriction, mucus secretion and airway remodeling. M3受体分布于炎症细胞,气道平滑肌和粘膜下腺,能介导支气管收缩,粘液分泌和气道重塑。