These orient themselves so that a fluid-filled cavity, the blastocoel, forms inside the mass of cells. 这些细胞进行自我调整,以致在细胞群内部形成一个充满液体的腔,即囊胚腔。
Transcripts for LIFR were detected within morula and blastocyst-stage embryos, while the LIF mRNA was only found in blastocysts ( from early to fully expanded blastocoel cavities), indicating that embryo-derived LIF can act in an autocrine manner on the process of blastocyst formation. 结果显示,LIFR在桑椹期和胚泡期胚胎中均有表达,而LIFmRNA仅在胚泡期出现,这表明胚源性LIF可通过自分泌来调节胚泡的形成。